Date published: 2025-9-6
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SMARCD2 Antibody (F-34) - Western Blotting - Image 368238
SMARCD2 抗体 (F-34): sc-101162. Jurkat (A), THP-1 (B), COLO 205 (C), RAW 264. 7 (D), NIH/3T3 (E) 和 PC-12 (F) 全细胞裂解液中 SMARCD2 表达的 Western 印迹分析.
SMARCD2 抗体 (F-34): sc-101162. Jurkat (A), THP-1 (B), COLO 205 (C), RAW 264. 7 (D), NIH/3T3 (E) 和 PC-12 (F) 全细胞裂解液中 SMARCD2 表达的 Western 印迹分析.

SMARCD2 抗体 (F-34): sc-101162

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说明书
  • SMARCD2 抗体 F-34 是小鼠单克隆 IgG2a κ，SMARCD2抗体, 在6篇文献中引用，规格为100 µg/ml
  • 与human起源的SMARCD2的C-terminal区域
  • 推荐用于 mouse, rat 和 human 来源的SMARCD2 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取SMARCD2 (F-34): sc-101162的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG2a BP-HRP 是 SMARCD2 抗体 (F-34) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与SMARCD2 抗体 (F-34) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 SMARCD 抗体 包括 SMARCD3

SMARCD2抗体（F-34）是一种IgG2a κ小鼠单克隆SMARCD2抗体（也称为SMARCD2抗体），可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人源的SMARCD2蛋白。SMARCD2抗体（F-34）是非偶联的抗SMARCD2抗体。SMARCD2（SWI/SNF相关、基质相关、肌动蛋白依赖性染色质调节因子，D亚家族，成员2），也称为Rsc6p、PRO2451、BAF60B（BRG1相关因子60B）或CRACD2，是SMARCD家族的成员，包含一个SWIB结构域。SMARCD2在肝脏、肌肉、胰腺、肺和胎盘中表达，定位于细胞核，是ATP依赖性染色质重塑复合物SWI/SNF的组成部分，被认为在核小体重塑中发挥作用。SWI/SNF复合物通过以ATP依赖的方式重塑核小体结构参与转录激活。SMARCD2是酿酒酵母蛋白Swp73的同源物，是酵母Swi/Snf复合物的组成部分，对转录激活是必需的。由于存在选择性剪接事件，SMARCD2存在两种异构体。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SMARCD2 抗体 (F-34) 参考文献:

  1. 人类 BAF60b（SWI/SNF 复合物的一个亚基）与第 17 号染色体上的甲状腺激素受体相互作用蛋白-1 基因之间物理联系的进化保护证据。  |  Surabhi, RM., et al. 1999. Genome. 42: 545-9. PMID: 10382302
  2. 人类乳腺癌细胞系和其他恶性肿瘤中 SWI/SNF 蛋白表达的特征。  |  Decristofaro, MF., et al. 2001. J Cell Physiol. 186: 136-45. PMID: 11147808
  3. 通过芯片测定年龄, 性别和力量训练对人体肌肉基因表达的影响。  |  Roth, SM., et al. 2002. Physiol Genomics. 10: 181-90. PMID: 12209020
  4. 通过 cDNA 微阵列基因表达分析电离辐照对人类食管癌细胞系的影响。  |  Bo, H., et al. 2004. J Nippon Med Sch. 71: 172-80. PMID: 15226608
  5. SWI/SNF染色质重塑复合物的SMARCD2亚基通过CEBPε依赖机制介导粒细胞生成。  |  Priam, P., et al. 2017. Nat Genet. 49: 753-764. PMID: 28369034
  6. 染色质重塑因子SMARCD2调节控制中性粒细胞分化的转录网络。  |  Witzel, M., et al. 2017. Nat Genet. 49: 742-752. PMID: 28369036
  7. 编码染色质重塑因子的SMARCD2中的新型移码常染色体隐性功能丧失突变介导粒细胞生成。  |  Yucel, E., et al. 2021. J Clin Immunol. 41: 59-65. PMID: 33025377
  8. 一种新型SMARCD2突变可破坏中性粒细胞成熟和功能，其临床和转录物特征。  |  Dotta, L., et al. 2023. Pediatr Blood Cancer. 70: e30671. PMID: 37712719
  9. 哺乳动物 SWI/SNF 复合物的多样性和特化。  |  Wang, W., et al. 1996. Genes Dev. 10: 2117-30. PMID: 8804307
  10. 哺乳动物 SW1/SNF 复合物的成分--大鼠 BAF60b 的基因结构及其与生长激素基因和转录因子 SUG/ 蛋白酶体 p45 基因的物理联系。  |  Nomoto, K., et al. 1997. Gene. 202: 157-65. PMID: 9427560
  11. 人类基因组中分布着五个与 SWI/SNF 相关, 与基质缔合作用相关, 依赖肌动蛋白的染色质调控因子（SMARC）基因。  |  Ring, HZ., et al. 1998. Genomics. 51: 140-3. PMID: 9693044
  12. 大鼠睾丸细胞粘附分子 1（TCAM-1）的基因结构及其与生长激素和 BAF60b（SWI/SNF 复合物的一个组成部分）编码基因的物理联系。  |  Ono, M., et al. 1999. Gene. 226: 95-102. PMID: 9889334

订购信息

产品名称产品编号规格价格数量收藏夹

SMARCD2 抗体 (F-34)

sc-101162
100 µg/ml
$333.00

SMARCD2 (F-34): m-IgG Fc BP-HRP 套装

sc-539736
100 µg Ab; 10 µg BP
$354.00

SMARCD2 (F-34): m-IgG2a BP-HRP 套装

sc-546776
100 µg Ab; 10 µg BP
$354.00

Does this antibody have specificity for SMARCD2 over SMARCD3/1?

Asked by: JBC_JHU
Thank you for your question. It would be helpful if you could call us directly at 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2021-12-10

Can I get free test sample of this antibody?

Asked by: Bin Lu
For a limited time, we are offering a free 10 µg sample of this antibody. Please contact our Technical Service Department if you would like to test the antibody before placing your order. Please call us toll-free at (800) 457-3801 option 2, e-mail <scbt@scbt.com>, or use the live chat on our website.
Answered by: Technical Support
Date published: 2017-09-28

Can sc-101162: SMARCD2 (F-34) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, sc-101162: SMARCD2 (F-34) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 1 out of 5 by from it works, but not very good!I tested using mouse ES cells. The antibody works for western blot. But not very well.
Date published: 2017-08-10
Rated 4 out of 5 by from Works good for ChIPI tested this antibody for CHIP assay in myoblast and works well
Date published: 2016-12-14
Rated 5 out of 5 by from Good specificity in WB in mouse transfectedGood specificity in WB in mouse transfected 293T and Jurkat whole cell lysates. -SCBT QC
Date published: 2015-05-01
Rated 5 out of 5 by from Strong band in WB in HeLa nuclear extractStrong band in WB in HeLa nuclear extract. -SCBT QC
Date published: 2015-02-27
Rated 5 out of 5 by from Produced beautiful immunoperoxidase nuclearProduced beautiful immunoperoxidase nuclear staining in formalin-fixed, paraffin-embedded human breast tissue. -SCBT QC
Date published: 2015-01-10
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SMARCD2 抗体 (F-34) is rated 4.0 out of 5 by 5.
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