Date published: 2026-10-17

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RARγ/Retinoic Acid Receptor γ 抗体 (H-6): sc-398065

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说明书
  • RARγ/Retinoic Acid Receptor γ 抗体 H-6 是小鼠单克隆 IgG1 κ,RARγ/Retinoic Acid Receptor γ抗体, 在1篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的RARγ的C-terminus的氨基酸417-454之间
  • RARγ/Retinoic Acid Receptor γ 抗体 (H-6) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 RARγ1 and RARγ2
  • 抗RARγ/Retinoic Acid Receptor γ抗体(H-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-398065 X, 200 µg/0.1 ml)
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是RARγ/Retinoic Acid Receptor γ Antibody (H-6) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与RARγ/Retinoic Acid Receptor γ Antibody (H-6) 打包提供(请参阅下面的订购信息)。
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関連項目

RARγ抗体(H-6)是一种IgG1 κ小鼠单克隆RAR gamma抗体(也称为RARG抗体,或维甲酸受体gamma抗体),可通过WB、IP、IF、IHC(P)和ELISA检测人类来源的RAR γ蛋白。RARγ抗体(H-6)既有非偶联型抗RAR γ抗体形式,也有多种偶联型抗RAR γ抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。类维生素A是维生素A(视黄醇)的代谢产物,是脊椎动物发育和组织分化过程中重要的信号分子。维甲酸受体(RARs)和类维生素A X受体(RXRs)是核转录因子,可调节类维生素A(RA)对基因表达的影响。大多数类维生素A形式(包括全反式RA、9-顺式RA、4oxo RA和3,4二氢RA)激活RAR家族成员,而RXR家族成员仅由9-顺式RA激活。RA与RARs结合,诱导受体构象发生变化,从而允许DNA结合和特定基因转录增加。RAR家族成员包括RARα、RARβ和RARγ,它们与甲状腺激素受体、维生素D3受体和蜕皮激素受体属于同一类核转录因子。类维生素A受体的表达具有组织特异性;皮肤表达RARγ和RXRα。RARγ和RXRβ的表达在肺癌中有所降低。人类RARγ基因定位于染色体12q13。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) 参考文献:

  1. TSLP在皮肤中的表达通过RARγ-RXR途径介导。  |  Mihály, J., et al. 2016. Immunobiology. 221: 161-5. PMID: 26531761
  2. 了解RARγ激动剂对人类骨软骨瘤外植体的作用。  |  Garcia, SA., et al. 2020. Int J Mol Sci. 21: PMID: 32294904
  3. 局部维生素 D 受体拮抗剂/部分兴奋剂治疗通过 RARγ 信号通路诱导表皮过度增殖  |  Lucas, R., et al. 2021. Dermatology. 237: 197-203. PMID: 32866959
  4. RARγ激活通过OAS-RNase L先天免疫途径使人类骨髓瘤细胞对卡非佐米治疗敏感。  |  Wang, Q., et al. 2022. Blood. 139: 59-72. PMID: 34411225
  5. 合成维甲酸通过诱导 RARγ 转运介导的张力降低和染色质解旋杀死耐药性癌症干细胞  |  Zhang, Y., et al. 2022. Adv Sci (Weinh). 9: e2203173. PMID: 36031407
  6. 维甲酸和RARγ通过调节翻译起始维持卫星细胞的静止状态。  |  Luo, W., et al. 2022. Cell Death Dis. 13: 838. PMID: 36175396
  7. 视黄酸受体γ(RARγ)通过正反馈激活 NF-κB 通路促进人类骨关节炎软骨破坏。  |  Yu, YW., et al. 2022. Mediators Inflamm. 2022: 1875736. PMID: 36387933
  8. 通过劫持RARα控制的程序,RARβ和RARγ核受体的协同激活可在干细胞分化过程中恢复细胞分化。  |  Koshy, A., et al. 2023. Life Sci Alliance. 6: PMID: 36446525
  9. RARγ复合体的表观遗传学破坏削弱了其功能,从而无法标记前列腺癌中恩杂鲁胺敏感性所需的AR增强子相互作用。  |  Wani, SA., et al. 2024. bioRxiv.. PMID: 38168185
  10. 星形胶质细胞 RARγ 在维甲酸诱导的慢性抑郁症中介导海马星形胶质细胞增多和神经发生缺陷  |  Huang, H., et al. 2024. Neuropsychopharmacology. 50: 419-431. PMID: 39242924

订购信息

产品名称产品编号规格价格数量收藏夹

RARγ/Retinoic Acid Receptor γ 抗体 (H-6)

sc-398065
200 µg/ml
$322.00

RARγ/Retinoic Acid Receptor γ (H-6): m-IgG Fc BP-HRP 套装

sc-530687
200 µg Ab; 10 µg BP
$361.00

RARγ/Retinoic Acid Receptor γ (H-6): m-IgGκ BP-HRP 套装

sc-524209
200 µg Ab, 40 µg BP
$361.00

RARγ/Retinoic Acid Receptor γ (H-6): m-IgG1 BP-HRP 套装

sc-544199
200 µg Ab; 20 µg BP
$361.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) X

sc-398065 X
200 µg/0.1 ml
$322.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) AC

sc-398065 AC
500 µg/ml, 25% agarose
$424.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) HRP

sc-398065 HRP
200 µg/ml
$322.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) FITC

sc-398065 FITC
200 µg/ml
$336.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) PE

sc-398065 PE
200 µg/ml
$349.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) Alexa Fluor® 488

sc-398065 AF488
200 µg/ml
$364.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) Alexa Fluor® 546

sc-398065 AF546
200 µg/ml
$364.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) Alexa Fluor® 594

sc-398065 AF594
200 µg/ml
$364.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) Alexa Fluor® 647

sc-398065 AF647
200 µg/ml
$364.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) Alexa Fluor® 680

sc-398065 AF680
200 µg/ml
$364.00

RARγ/Retinoic Acid Receptor γ 抗体 (H-6) Alexa Fluor® 790

sc-398065 AF790
200 µg/ml
$364.00

RARγ/Retinoic Acid Receptor γ (H-6) 中和勝肽

sc-398065 P
100 µg/0.5 ml
$69.00

What application is the blocking peptide sc-398065 P appropriate for?

Asked by: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by XueP from Great feature!I got this free sample 1 month ago, this antibody works very well in MCF7 cell and RAR knock down also works well.
Date published: 2017-07-25
Rated 5 out of 5 by tianshi0xiu from It's goodIt's good to use,but sometime there is not only one band
Date published: 2017-06-25
Rated 5 out of 5 by TS from Very good Western blot data of RAR expressionVery good Western blot data of RAR expression in PMA-treated A-431 nuclear extract and HeLa whole cell lysate . -SCBT QC
Date published: 2013-06-29
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RARγ/Retinoic Acid Receptor γ 抗体 (H-6) is rated 5.0 out of 5 by 3.
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