Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

Phox2a 抗体 (37K-2): sc-81978

4.6(5)
寫評論提問

说明书
  • Phox2a 抗体 37K-2 是小鼠单克隆 IgG2a κ,Phox2a抗体, 在7篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组Phox2a
  • 推荐用于 mouse, rat 和 human 来源的Phox2a WB, IP, IF 和 ELISA检测
  • 关于如何获取Phox2a (37K-2): sc-81978免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRP是Phox2a Antibody (37K-2) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Phox2a Antibody (37K-2) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

Phox2a抗体(37K-2)是一种IgG2a κ小鼠单克隆Phox2a抗体(也称为Phox2a抗体),可通过蛋白质印迹法(WB)、免疫沉淀法(IP)、免疫荧光法(IF)和酶联免疫吸附测定法(ELISA)检测小鼠、大鼠和人源性的Phox2a蛋白。Phox2a抗体(37K-2)为非偶联抗Phox2a抗体。Phox2a(也称为Arix1)和Phox2b是密切相关的配对同源结构域转录因子,对于发育中的交感、副交感和肠神经节中神经元的分化是必不可少的。所有肠神经系统细胞均来源于神经嵴,所有未分化的细胞最初均表达Phox2b。沿着神经元谱系开始分化的细胞继续表达Phox2b,并开始表达Phox2a。Phox2b是大脑中所有中枢和非周围去甲肾上腺素能中心分化所必需的。相比之下,Phox2a仅控制大脑中主要的去甲肾上腺素能中心--蓝斑的分化。Phox2a和Phox2b对于调节内源性酪氨酸羟化酶和多巴胺-β-羟化酶至关重要,这些酶在神经嵴细胞中瞬时表达。此外,Phox2蛋白足以促进交感神经元的生成。编码Phox2a的基因位于人类染色体11q13.3-q13.4上。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Phox2a 抗体 (37K-2) 参考文献:

  1. 神经嵴干细胞中的 Phox2 蛋白对神经递质特性的指定  |  Lo, L., et al. 1999. Neuron. 22: 693-705. PMID: 10230790
  2. 同源基因 Phox2b 对自主神经嵴衍生物的发育至关重要。  |  Pattyn, A., et al. 1999. Nature. 399: 366-70. PMID: 10360575
  3. Phox2 同源域蛋白足以促进交感神经元的发育。  |  Stanke, M., et al. 1999. Development. 126: 4087-94. PMID: 10457017
  4. 胚胎小鼠肠道中未分化的神经嵴衍生细胞和不同类别的肠道神经元表达 Ret, p75(NTR), Phox2a, Phox2b 和酪氨酸羟化酶免疫反应。  |  Young, HM., et al. 1999. Dev Dyn. 216: 137-52. PMID: 10536054
  5. 同源基因 Phox2b 对中枢去甲肾上腺素能表型的规定  |  Pattyn, A., et al. 2000. Mol Cell Neurosci. 15: 235-43. PMID: 10736201
  6. 将 ARIX 同源域基因绘制到小鼠 7 号染色体和人类 11q13 号染色体上。  |  Johnson, KR., et al. 1996. Genomics. 33: 527-31. PMID: 8661014

订购信息

产品名称产品编号规格价格数量收藏夹

Phox2a 抗体 (37K-2)

sc-81978
100 µg/ml
$333.00

Phox2a (37K-2): m-IgG Fc BP-HRP 套装

sc-539677
100 µg Ab; 10 µg BP
$354.00

Phox2a (37K-2): m-IgG2a BP-HRP 套装

sc-546747
100 µg Ab; 10 µg BP
$354.00

I am using Phox2a (37K-2): sc-81978 for immunofluorescence, what dilution of this antibody should I use?

Asked by: Professor Griffin
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
  • y_2025, m_8, d_27, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_81978, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 100ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great choice for Western Blot and ChIPAntibody has been used for Western Blot and Chromatin Immunoprecipitation in published research. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Clear single band was detectedProtein lysates from Neuroblastoma cells SH-SY5Y (PHOX2A negative) and SH-EP (PHOX2A positive) were loaded, and PHOX2A antibody (37K-2) was tested in different antibody diluents by western blotting.
Date published: 2019-01-26
Rated 4 out of 5 by from Band seen in WB using PCBand seen in WB using PC-12 whole cell lysate. -SCBT QC
Date published: 2015-05-26
Rated 4 out of 5 by from Strong bands detected in WB using SHStrong bands detected in WB using SH-SY5Y and IMR-32 whole cell lysates. -SCBT Publication Review
Date published: 2015-05-22
Rated 5 out of 5 by from Produced excellent immunofluorescence nuclearProduced excellent immunofluorescence nuclear staining in paraformaldehyde-fixed HeLa cells. -SCBT QC
Date published: 2015-03-16
  • y_2025, m_8, d_27, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_81978, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
Phox2a 抗体 (37K-2) is rated 4.6 out of 5 by 5.
  • y_2025, m_8, d_27, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_5
  • loc_zh_CN, sid_81978, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 125ms
  • REVIEWS, PRODUCT