Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PDE10A Antibody (G-7) is a high quality monoclonal PDE10A antibody suitable for the detection of the PDE10A protein of mouse, rat and human origin. PDE10A Antibody (G-7) is available as both the non-conjugated anti-PDE10A antibody form, as well as multiple conjugated forms of anti-PDE10A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. PDE10A (phosphodiesterase 10A) is a striatum-enriched dual-substrate phosphodiesterase that participates in signal transduction by regulating the concentration of cyclic nucleotides. Localized to soluble cellular fractions within the cytoplasm, PDE10A can hydrolyze both cGMP and cAMP to the corresponding nucleoside 5-prime monophosphate, thereby eliminating cGMP- and cAMP-mediated intracellular signaling. Through its ability to hydrolyze cyclic nucleotides, PDE10A regulates the excitability of medium spiny neurons located in the striatum. PDE10A is expressed abundantly in the putamen and caudate nuclear regions of the testis and brain, with moderate expression observed in the pituitary gland, thalamus and cerebellum. PDE10A contains an N-terminal regulatory domain and a C-terminal catalytic domain which has two putative divalent metal binding sites. Two isoforms exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences