Date published: 2025-9-7

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PCDHA8 抗体 (A-9): sc-514530

5.0(1)
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说明书
  • PCDHA8 抗体 A-9 是小鼠单克隆 IgM (kappa轻链),PCDHA8抗体,规格为200 µg/ml
  • 特异性抗原位于rat物种的PCDHA8的内部区域内的氨基酸573-588之间
  • 推荐用于 mouse 和 rat 来源的PCDHA8 WB, IP, IF 和 ELISA检测
  • 关于如何获取PCDHA8 (A-9): sc-514530免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成PCDHA8 抗体 (A-9)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    PCDHA8抗体(A-9)是一种IgM κ型小鼠单克隆PCDHA8抗体(也称为PCDHA8抗体),可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测到小鼠和大鼠来源的PCDHA8蛋白。PCDHA8抗体(A-9)为非偶联形式的抗PCDHA8抗体。原钙粘蛋白是一大类钙粘蛋白样细胞粘附蛋白,参与大脑中神经元连接的建立和维护。有三个原钙粘蛋白基因簇,分别命名为α、β和γ,均含有多个串联排列的基因。PCDHA8(原钙粘蛋白α8)是一种含有950个氨基酸的单通道I型膜蛋白,包含六个钙粘蛋白结构域,由位于人类5号染色体上原钙粘蛋白α基因簇内的基因编码。PCDHA8以多种选择性剪接异构体的形式存在,作为潜在的钙依赖性细胞粘附蛋白,可能参与大脑中神经元连接的建立和维护。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    PCDHA8 抗体 (A-9) 参考文献:

    1. 编码多个外显子的大外显子是原粘连蛋白基因的一个特征。  |  Wu, Q. and Maniatis, T. 2000. Proc Natl Acad Sci U S A. 97: 3124-9. PMID: 10716726
    2. 钙粘蛋白超家族基因:功能, 基因组组织和神经系统多样性。  |  Yagi, T. and Takeichi, M. 2000. Genes Dev. 14: 1169-80. PMID: 10817752
    3. 通过对粘附素超家族的系统进化分析,可以确定除了几个单独的成员外,还有六个主要的亚家族。  |  Nollet, F., et al. 2000. J Mol Biol. 299: 551-72. PMID: 10835267
    4. 原粘连蛋白研究的最新进展。  |  Suzuki, ST. 2000. Exp Cell Res. 261: 13-8. PMID: 11082270
    5. 小鼠和人类原粘连蛋白基因簇的 DNA 序列比较分析。  |  Wu, Q., et al. 2001. Genome Res. 11: 389-404. PMID: 11230163
    6. 广泛的连锁不平衡, 16.7 千碱基的共同缺失以及人类原粘连蛋白 alpha 簇平衡选择的证据。  |  Noonan, JP., et al. 2003. Am J Hum Genet. 72: 621-35. PMID: 12577201
    7. 原粘连蛋白-α基因簇长程调控元件的鉴定  |  Ribich, S., et al. 2006. Proc Natl Acad Sci U S A. 103: 19719-24. PMID: 17172445

    订购信息

    产品名称产品编号规格价格数量收藏夹

    PCDHA8 抗体 (A-9)

    sc-514530
    200 µg/ml
    $316.00

    PCDHA8 (A-9) 中和勝肽

    sc-514530 P
    100 µg/0.5 ml
    $68.00

    SCBT QC Lab gave validation in rats and mice, but the figure notes said but the 'Antibody detects PCDHA8 at around 100 KDa in rat cerebellum tissue (right) and in mouse brain tissue (right) to a lesser extent'. Which lane was rat?

    Asked by: yiqing
    Thank you for your question.PCDHA8 Antibody (A-9): sc-514530 can be used to detect rat and mouse. Our official website only uploaded the WB experiment result graphs of rat cerebellar tissue for reference. If you have any questions, please contact our technical service department. Thank you.
    Answered by: Jiajun Z
    Date published: 2024-05-13

    What application is the blocking peptide sc-514530 P appropriate for?

    Asked by: AbPolly
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Works well in detecting rat and mouse PCDHA8Antibody detects PCDHA8 at around 100 KDa in rat cerebellum tissue (right) and in mouse brain tissue (right) to a lesser extent. (Note that lower band in left lane is mouse IgG heavy chain) -SCBT QC
    Date published: 2023-09-14
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    PCDHA8 抗体 (A-9) is rated 5.0 out of 5 by 1.
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