Date published: 2025-9-10

021-6093-6350

SCBT Portrait Logo
Seach Input

paxillin 抗体 (D-8): sc-365059

4.5(4)
寫評論提問

说明书
  • paxillin抗体(D-8)是小鼠单克隆IgG1 κ, 在6篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的paxillin的N-terminus附近的氨基酸17-47之间
  • 推荐用于 mouse, rat 和 human 来源的α,β, γ isoforms of paxillin WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine and canine
  • 看 paxillin (B-2): sc-365379,可查看有标记的 paxillin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是paxillin Antibody (D-8) for WB applications. 的首选辅助检测试剂,这些试剂现与paxillin Antibody (D-8) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

Paxillin是一种位于细胞骨架的粘着斑磷酸蛋白。已经证明,Paxillin的磷酸化发生在PDGF治疗、v-src转化或整合素交联反应中。FAK(粘着斑激酶)和PYK2已被证明可以磷酸化paxillin。FAK在体外特异性磷酸化paxillin的Tyr 118。然而,FAK磷酸化似乎不是paxillin募集到细胞粘附位点所必需的。Paxillin可能在信号转导、细胞形态调节以及结构和信号分子募集到粘着斑中发挥作用。已经证明,有丝分裂细胞中paxillin的量通过蛋白水解下调而减少,并且paxillin在有丝分裂过程中可选择性地磷酸化丝氨酸而不是酪氨酸和丝氨酸。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

paxillin 抗体 (D-8)

sc-365059
200 µg/ml
$316.00

paxillin (D-8): m-IgG Fc BP-HRP 套装

sc-540304
200 µg Ab; 10 µg BP
$354.00

paxillin (D-8): m-IgG1 BP-HRP 套装

sc-542026
200 µg Ab; 20 µg BP
$354.00

paxillin (D-8) 中和勝肽

sc-365059 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-365059 P appropriate for?

Asked by: Dr Ninau Qelp
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_27, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_365059, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 81ms
  • QUESTIONS, PRODUCT
Rated 3 out of 5 by from Good for WB, but NOT for IF!I bought this to use mainly for IF, because the product sheet IF picture looked good. Western blots do work (so I gave 3 stars), but IF had absolutely no signal. I tested it twice alongside 5 other Santa Cruz mouse monoclonal antibodies and this was the only one that absolutely did not work (4% PFA fixation,1/50 primary antibody dilution). I then tested it in cells with GFP-Zyxin so I could see that adhesions were there but the anti-paxillin staining was not. Super disappointed to have wasted $ on this one.
Date published: 2019-04-19
Rated 5 out of 5 by from positive western blot staining for paxillinWe used this antibody for paxillin expression detection with western blot. We got a positive band at the correct molecular weight for HeLa cells
Date published: 2017-01-31
Rated 5 out of 5 by from Excellent immunofluorescence focal adhesionsExcellent immunofluorescence focal adhesions and membrane staining in formalin-fixed HepG2 cells. -SCBT QC
Date published: 2015-01-29
Rated 5 out of 5 by from Produced positive Western Blot data of paxillinProduced positive Western Blot data of paxillin expression in CCD-1064Sk whole cell lysate. -SCBT QC
Date published: 2014-05-27
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_365059, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
paxillin 抗体 (D-8) is rated 4.5 out of 5 by 4.
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_365059, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 103ms
  • REVIEWS, PRODUCT