Date published: 2025-9-8

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osteocalcin 抗体 (D-11): sc-390877

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说明书
  • osteocalcin抗体(D-11)是小鼠单克隆IgG2b κ, 在58篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的代表全长osteocalcin的氨基酸1-95
  • osteocalcin 抗体 (D-11) 推荐用于 WB, IP, IF 和 ELISA,检测 osteocalcin of mouse, rat and human origin and osteocalcin-2 and osteocalcin-related protein of mouse origin
  • 抗osteocalcin抗体(D-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取osteocalcin (D-11): sc-390877免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRP是osteocalcin Antibody (D-11) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与osteocalcin Antibody (D-11) 打包提供(请参阅下面的订购信息)。

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関連項目

骨钙蛋白抗体(D-11)是一种IgG2b κ型小鼠单克隆骨钙蛋白抗体,它能够通过WB、IP、IF和ELISA技术检测小鼠、大鼠和人类的骨钙蛋白,以及小鼠来源的骨钙蛋白-2和骨钙蛋白相关蛋白。骨钙蛋白抗体(D-11)既提供非偶联形式的抗骨钙蛋白抗体提供,也提供多种偶联形式的抗骨钙蛋白抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。骨γ-羧基谷氨酸(Gla)蛋白,也被称为BGLAP、BGP或骨钙蛋白,是骨中一种丰富的非胶原蛋白成分,由成骨细胞产生。在小鼠中,骨钙蛋白由一组3个基因组成,分别是OG1、OG2和ORG,所有这些基因都位于23Kb的基因组DNA范围内。人类骨钙蛋白是一种高度保守的、含有46-50个氨基酸的单链蛋白质,其中含有三个维生素K依赖性的γ-羧基谷氨酸残基。在矿物质沉积时,骨钙蛋白短暂地出现在胚胎骨骼中,并以钙依赖性的方式与羟基磷灰石结合。此外,骨钙蛋白是矿化成人骨骼中发现的最丰富的非胶原蛋白之一。1号染色体上骨钙蛋白基因位点的遗传变异会影响绝经后女性的骨矿物质密度(BMD)水平,并可能使某些女性更容易患上骨质疏松症。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

osteocalcin 抗体 (D-11) 参考文献:

  1. 骨钙素:人类基因 BGLAP 的遗传和物理图谱及其在绝经后骨质疏松症中的潜在作用。  |  Raymond, MH., et al. 1999. Genomics. 60: 210-7. PMID: 10486212
  2. 骨钙素诱导人破骨细胞趋化, 基质蛋白分泌和钙介导的细胞内信号传导。  |  Chenu, C., et al. 1994. J Cell Biol. 127: 1149-58. PMID: 7962073
  3. 人类骨 GLA 蛋白(BGP/骨钙蛋白)前肽抗体的制备和特性鉴定及其在骨细胞免疫细胞化学中的应用。  |  Kasai, R., et al. 1994. Bone Miner. 25: 167-82. PMID: 8086856
  4. 小鼠骨钙素基因簇包含三个基因,具有两种不同的空间和时间表达模式。  |  Desbois, C., et al. 1994. J Biol Chem. 269: 1183-90. PMID: 8288580
  5. 原发性骨肿瘤中骨钙素的表达--原位杂交和免疫组化研究  |  Park, YK., et al. 1995. J Korean Med Sci. 10: 263-8. PMID: 8593206
  6. 骨髓基质脂肪细胞的骨钙素(BGP), 基因表达和蛋白质生成。  |  Benayahu, D., et al. 1997. Biochem Biophys Res Commun. 231: 442-6. PMID: 9070297
  7. 五种骨钙素测定法比较:示踪剂特异性, 片段干扰和校准。  |  Colford, J., et al. 1997. Clin Chem. 43: 1240-1. PMID: 9216464
  8. 使用或不使用维生素 D3 进行绝经后激素替代治疗期间的生化骨标志物和骨矿物质密度:一项前瞻性, 对照, 随机研究。  |  Heikkinen, AM., et al. 1997. J Clin Endocrinol Metab. 82: 2476-82. PMID: 9253321
  9. 骨钙素基因:骨骼特异性转录控制多种参数的模型。  |  Stein, GS., et al. 1997. Mol Biol Rep. 24: 185-96. PMID: 9291092

订购信息

产品名称产品编号规格价格数量收藏夹

osteocalcin 抗体 (D-11)

sc-390877
200 µg/ml
$316.00

osteocalcin (D-11): m-IgG Fc BP-HRP 套装

sc-526202
200 µg Ab; 10 µg BP
$354.00

osteocalcin (D-11): m-IgG2b BP-HRP 套装

sc-549692
200 µg Ab; 10 µg BP
$354.00

osteocalcin 抗体 (D-11) AC

sc-390877 AC
500 µg/ml, 25% agarose
$416.00

osteocalcin 抗体 (D-11) HRP

sc-390877 HRP
200 µg/ml
$316.00

osteocalcin 抗体 (D-11) FITC

sc-390877 FITC
200 µg/ml
$330.00

osteocalcin 抗体 (D-11) PE

sc-390877 PE
200 µg/ml
$343.00

osteocalcin 抗体 (D-11) Alexa Fluor® 488

sc-390877 AF488
200 µg/ml
$357.00

osteocalcin 抗体 (D-11) Alexa Fluor® 546

sc-390877 AF546
200 µg/ml
$357.00

osteocalcin 抗体 (D-11) Alexa Fluor® 594

sc-390877 AF594
200 µg/ml
$357.00

osteocalcin 抗体 (D-11) Alexa Fluor® 647

sc-390877 AF647
200 µg/ml
$357.00

osteocalcin 抗体 (D-11) Alexa Fluor® 680

sc-390877 AF680
200 µg/ml
$357.00

osteocalcin 抗体 (D-11) Alexa Fluor® 790

sc-390877 AF790
200 µg/ml
$357.00

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with osteocalcin (D-11): sc-390877 monoclonal antibody?

Asked by: jenni
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGκ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 15
Date published: 2017-01-18
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Rated 5 out of 5 by from the primary antibody is greatRencetly, I applied for the free primary antibody, named osteocalcin, and the result is great, so the the primary antibody must be first chioce primary antibody from now o.
Date published: 2017-12-21
Rated 5 out of 5 by from clear bandObtained a single clear band in Western Blot with 293T cells,1:400 dilution .
Date published: 2017-05-31
Rated 5 out of 5 by from clean stripsWe use it in human bone marrow tissue extract., these has worked very well in WB
Date published: 2017-05-02
Rated 5 out of 5 by from specific stainingHighly specific staining of paraffin-embedded human skin tissue showing cytoplasmic staining of epidermal cells in IF.
Date published: 2017-02-25
Rated 5 out of 5 by from Strong western !!Very clear western blot data; strong,specific signal
Date published: 2017-02-01
Rated 5 out of 5 by from Works Great!This antibody works great in western blot analysis of osteocalcin expression in human bone marrow tissue extract.
Date published: 2016-12-23
Rated 5 out of 5 by from Great Western blot data of osteocalcin expressionGreat Western blot data of osteocalcin expression in human bone marrow tissue extract. -SCBT QC
Date published: 2013-04-28
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osteocalcin 抗体 (D-11) is rated 5.0 out of 5 by 7.
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