NGFR p75 Antibody (2B2.55): sc-71694
- NGFR p75 Antibody (2B2.55) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against NGFR p75 from A875 melanoma cells of human origin
- recommended for detection of NGFR p75 of human and feline origin by WB, IP, IF, IHC(P) and FCM; non cross-reactive with mouse or rat NGFR p75
- See NGFR p75 (B-1): sc-271708 for NGFR p75 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NGFR p75 Antibody (2B2.55) for WB and IHC(P) applications. These reagents are now offered in bundles with NGFR p75 Antibody (2B2.55) (see ordering information below).
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NGFR p75 Antibody (2B2.55) is a mouse monoclonal IgG1 antibody that detects NGFR p75 in human and feline samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). NGFR p75, also known as the low-affinity nerve growth factor receptor, plays a crucial role in the nervous system by modulating the effects of neurotrophic factors, particularly nerve growth factor (NGF). NGFR p75 is primarily located on the surface of neurons and glial cells, where NGFR p75 acts as a co-receptor that enhances the signaling of high-affinity receptors like TrkA. NGFR p75 is essential for the proper activation of TrkA, as NGFR p75 not only accelerates TrkA activation but also facilitates the recruitment of downstream signaling molecules, thereby amplifying the neurotrophic signals that are vital for neuronal survival, differentiation, and growth. The interaction between NGFR p75 and neurotrophic factors is significant because NGFR p75 ensures that neurons receive the necessary support for their development and maintenance, highlighting the importance of NGFR p75 in neurobiology and potential therapeutic applications in neurodegenerative diseases. NGFR p75 monoclonal antibody (2B2.55) is an invaluable tool for researchers studying neuronal signaling pathways and the intricate mechanisms of neurotrophic factor interactions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NGFR p75 Antibody (2B2.55) | sc-71694 | 200 µg/ml | $322.00 | |||
NGFR p75 Antibody (2B2.55): m-IgG Fc BP-HRP Bundle | sc-539392 | 200 µg Ab; 10 µg BP | $361.00 | |||
NGFR p75 Antibody (2B2.55): m-IgG1 BP-HRP Bundle | sc-541458 | 200 µg Ab; 20 µg BP | $361.00 |