m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred secondary detection reagent for MRP-L39 Antibody (F-10) for WB and IHC(P) applications. This reagent is now offered in a bundle with MRP-L39 Antibody (F-10) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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MRP-L39 Antibody (F-10) is a high quality monoclonal MRP-L39 antibody (also designated MRP-L39 antibody) suitable for the detection of the MRP-L39 protein of mouse, rat and human origin. MRP-L39 Antibody (F-10) is available as both the non-conjugated anti-MRP-L39 antibody form, as well as multiple conjugated forms of anti-MRP-L39 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L39 (mitochondrial ribosomal protein L39), also known as MRP-L5, L39mt or L5mt, is a 338 amino acid mitochondrial protein that exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-L39 exists as two isoforms produced by alternative splicing. Isoform one of MRP-L39 is ubiquitously expressed while isoform two is specifically expressed in heart. The gene encoding MRP-L39 maps to chromosome 21, which makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer′s disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21
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