Date published: 2025-9-8

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KLF6 抗体 (E-10): sc-365633

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说明书
  • KLF6 抗体 E-10 是小鼠单克隆 IgG1 κ,KLF6抗体, 在16篇文献中引用,规格为200 µg/ml
  • 免疫rat物种的KLF6的氨基酸28-201
  • KLF6 抗体 (E-10) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 KLF6
  • 抗KLF6抗体(E-10)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-365633 X, 200 µg/0.1 ml)
  • 关于如何获取KLF6 (E-10): sc-365633免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是KLF6 Antibody (E-10) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与KLF6 Antibody (E-10) 打包提供(请参阅下面的订购信息)。

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関連項目

KLF6抗体(E-10)是一种IgG1κ小鼠单克隆KLF6抗体,通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的KLF6蛋白。KLF6抗体(E-10)既可作为非缀合的抗KLF6抗体形式,也可作为多种缀合形式的抗KLF6-抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa-Fluor®缀合物。Krüppel锌指转录因子最初在果蝇中被鉴定为一种分割基因。Krüppel型锌指转录因子的哺乳动物家族包括一个在发育调控中重要的DNA结合蛋白的保守家族。Krüppel样因子6(KLF6)蛋白是一种核DNA结合蛋白。KLF6通过以p53非依赖性方式上调p21来减少细胞增殖。KLF6也被称为转录因子ZF9、B细胞衍生的1(BCD1)和核心启动子元件结合蛋白(COPEB)。KLF6主要在胎盘中表达,但也存在于脾脏、胸腺、前列腺、睾丸、小肠和结肠中。在胎盘中,KLF6、KLF4和妊娠糖蛋白在相同细胞类型的胎盘绒毛和膜中共同表达。编码人KLF6的基因定位于染色体10p15,在人类癌症的一个子集中发生突变。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

KLF6 抗体 (E-10) 参考文献:

  1. 肝细胞癌中肿瘤抑制因子Krüppel样因子6(KLF6)的失活或表达降低。  |  Pan, XC., et al. 2006. J Zhejiang Univ Sci B. 7: 830-6. PMID: 16972326
  2. KLF6 转录因子保护肝癌衍生细胞免于凋亡。  |  Sirach, E., et al. 2007. Cell Death Differ. 14: 1202-10. PMID: 17347668
  3. Krüppel样因子6(KLF6)可促进骨骼肌细胞增殖,以响应TGFβ/Smad3信号。  |  Dionyssiou, MG., et al. 2013. Skelet Muscle. 3: 7. PMID: 23547561
  4. 包含果蝇分节基因 Krüppel 编码的指状蛋白结构元素的核蛋白保守家族。  |  Schuh, R., et al. 1986. Cell. 47: 1025-32. PMID: 3096579
  5. 在杆状病毒表达系统中产生的果蝇 Krüppel 基因产物是一种能与 DNA 结合的核磷蛋白。  |  Ollo, R. and Maniatis, T. 1987. Proc Natl Acad Sci U S A. 84: 5700-4. PMID: 3112773
  6. 肝细胞KLF6表达会影响FXR信号传导和原发性硬化性胆管炎的临床过程。  |  Sydor, S., et al. 2020. Liver Int. 40: 2172-2181. PMID: 32462764
  7. 分离出编码与红细胞 Krüppel 样因子同源的功能性锌指蛋白的基因:确定了一个新的多基因家族。  |  Anderson, KP., et al. 1995. Mol Cell Biol. 15: 5957-65. PMID: 7565748
  8. 鉴定和表征一种在生长停滞期间表达的肠道富集克鲁珀尔样因子的编码基因。  |  Shields, JM., et al. 1996. J Biol Chem. 271: 20009-17. PMID: 8702718
  9. 人类红细胞克鲁佩尔样因子(EKLF)的分离, 基因组结构和表达。  |  Bieker, JJ. 1996. DNA Cell Biol. 15: 347-52. PMID: 8924208
  10. 与无 TATA 盒基因的核心启动子元件相互作用的新型人类锌指蛋白。  |  Koritschoner, NP., et al. 1997. J Biol Chem. 272: 9573-80. PMID: 9083102
  11. Zf9,一种在早期肝纤维化过程中体内上调的 Kruppel 样转录因子。  |  Ratziu, V., et al. 1998. Proc Natl Acad Sci U S A. 95: 9500-5. PMID: 9689109
  12. 人类基因 GLI-Kruppel 家族。  |  Ruppert, JM., et al. 1988. Mol Cell Biol. 8: 3104-13. PMID: 2850480

订购信息

产品名称产品编号规格价格数量收藏夹

KLF6 抗体 (E-10)

sc-365633
200 µg/ml
$316.00

KLF6 (E-10): m-IgG Fc BP-HRP 套装

sc-529416
200 µg Ab; 10 µg BP
$354.00

KLF6 (E-10): m-IgGκ BP-HRP 套装

sc-522302
200 µg Ab, 40 µg BP
$354.00

KLF6 抗体 (E-10) X

sc-365633 X
200 µg/0.1 ml
$316.00

KLF6 抗体 (E-10) AC

sc-365633 AC
500 µg/ml, 25% agarose
$416.00

KLF6 抗体 (E-10) HRP

sc-365633 HRP
200 µg/ml
$316.00

KLF6 抗体 (E-10) FITC

sc-365633 FITC
200 µg/ml
$330.00

KLF6 抗体 (E-10) PE

sc-365633 PE
200 µg/ml
$343.00

KLF6 抗体 (E-10) Alexa Fluor® 488

sc-365633 AF488
200 µg/ml
$357.00

KLF6 抗体 (E-10) Alexa Fluor® 546

sc-365633 AF546
200 µg/ml
$357.00

KLF6 抗体 (E-10) Alexa Fluor® 594

sc-365633 AF594
200 µg/ml
$357.00

KLF6 抗体 (E-10) Alexa Fluor® 647

sc-365633 AF647
200 µg/ml
$357.00

KLF6 抗体 (E-10) Alexa Fluor® 680

sc-365633 AF680
200 µg/ml
$357.00

KLF6 抗体 (E-10) Alexa Fluor® 790

sc-365633 AF790
200 µg/ml
$357.00

What secondary is best to use with KLF6 (E-10): sc-365633 monoclonal antibody?

Asked by: cjMara
Thank you for your question. While most anti-mouse IgG secondary antibodies are appropriate for use with KLF6 (E-10): sc-365633 mouse monoclonal IgG1, we recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 7
Date published: 2017-01-20
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Rated 5 out of 5 by from UsureI bought this antibody for WB & IHC, both works very well.
Date published: 2021-06-22
Rated 5 out of 5 by from very wellExcellent results in Western Blot with pig and mouse samples.
Date published: 2020-07-01
Rated 3 out of 5 by from 一般般啦能孵出目的条带,但是有杂带。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。
Date published: 2018-01-23
Rated 5 out of 5 by from いい抗体ですRAW264.7細胞のWhole-cell lysate (15 ug protein)を200倍希釈した抗体で検出
Date published: 2018-01-18
Rated 5 out of 5 by from Works in Embryonic Neural Tissue for IHCWas able to get working well in embryonic PFA fixed neural tissue 1:200 with Antigen Retrieval
Date published: 2017-08-17
Rated 5 out of 5 by from Strong WB dataReally nice western blot data; very strong signal !!
Date published: 2017-02-05
Rated 5 out of 5 by from Solid antibody!Looking to detect KLF6 in a Western blot? This is a great choice: strong and reliable, with consistent nice banding in WB.
Date published: 2017-01-09
Rated 5 out of 5 by from good antibodyGood antibody with clear signal and no background, the intensity of band is just right, not too strong not too weak
Date published: 2016-12-08
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KLF6 抗体 (E-10) is rated 4.7 out of 5 by 11.
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