KAT II Antibody (A-2): sc-515377
- KAT II Antibody (A-2) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 158-183 within an internal region of KAT II of human origin
- recommended for detection of KAT II of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KAT II Antibody (A-2) for WB applications. These reagents are now offered in bundles with KAT II Antibody (A-2) (see ordering information below).
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KAT II Antibody (A-2) is a mouse monoclonal IgG2a antibody that detects KAT II in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KAT II, a member of the class-I pyridoxal-phosphate-dependent aminotransferase family, plays a crucial role in lysine degradation, which is essential for maintaining amino acid homeostasis and energy metabolism within cells. This mitochondrial protein is predominantly expressed in the liver, but is also found in significant amounts in the heart, brain, kidney, pancreas, ovary, and testis, highlighting KAT II′s importance in various physiological processes across different tissues. KAT II catalyzes the conversion of L-2-aminoadipate and 2-oxoglutarate into 2-oxoglutaramate and L-glutamate, functioning as a homodimer to facilitate this reaction. KAT II′s ability to interact with other metabolic pathways underscores its significance in cellular metabolism and potential implications in metabolic disorders, making anti-KAT II antibody (A-2) a valuable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KAT II Antibody (A-2) | sc-515377 | 200 µg/ml | $322.00 | |||
KAT II Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-538781 | 200 µg Ab; 10 µg BP | $361.00 | |||
KAT II Antibody (A-2): m-IgGκ BP-HRP Bundle | sc-536451 | 200 µg Ab; 40 µg BP | $361.00 | |||
KAT II Antibody (A-2): m-IgG2a BP-HRP Bundle | sc-548406 | 200 µg Ab; 10 µg BP | $361.00 | |||
KAT II (A-2) Neutralizing Peptide | sc-515377 P | 100 µg/0.5 ml | $69.00 |