Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

JAK1 抗体 (B-3): sc-376996

4.3(7)
寫評論提問

说明书
  • JAK1 抗体 B-3 是小鼠单克隆 IgG1 κ,JAK1抗体, 在24篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列270-375位于human物种的JAK1的N-terminus
  • JAK1 抗体 (B-3) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 JAK1
  • 抗JAK1抗体(B-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取JAK1 (B-3): sc-376996免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是JAK1 Antibody (B-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与JAK1 Antibody (B-3) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

JAK1抗体(B-3)是一种IgG1 κ小鼠单克隆JAK1抗体(也被称为Janus激酶1抗体),能够通过WB、IP、IF和ELISA检测人类来源的JAK1蛋白。JAK1抗体(B-3)以非偶联的抗JAK1抗体形式提供,同时也以多种偶联形式的抗JAK1抗体提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。JAK1(Janus激酶1)属于非受体Janus酪氨酸激酶家族,在淋巴造血系统中调节活化细胞因子受体下游的一系列细胞功能。免疫学刺激,如干扰素和细胞因子,会诱导Stat转录因子招募到与细胞因子受体相关的JAK1。然后,JAK1使近端Stat因子磷酸化,这些因子随后二聚化,转位到细胞核并结合到目标基因启动子上游的顺式元件以调节转录。配体结合后,JAK1以相互依赖的方式发生酪氨酸磷酸化和催化激活。位于1022和1023位的酪氨酸残基的磷酸化被认为在催化事件的激活中起作用。典型的JAK-Stat途径通过刺激增殖、分化、存活和对病原体的宿主抗性,是维持正常免疫系统所必需的。改变JAK-Stat信号以减少细胞因子诱导的促炎反应代表了抗炎治疗的一个有吸引力的目标。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

JAK1 抗体 (B-3)

sc-376996
200 µg/ml
$316.00

JAK1 (B-3): m-IgG Fc BP-HRP 套装

sc-529953
200 µg Ab; 10 µg BP
$354.00

JAK1 (B-3): m-IgGκ BP-HRP 套装

sc-523144
200 µg Ab, 40 µg BP
$354.00

JAK1 (B-3): m-IgG1 BP-HRP 套装

sc-543783
200 µg Ab; 20 µg BP
$354.00

JAK1 抗体 (B-3) AC

sc-376996 AC
500 µg/ml, 25% agarose
$416.00

JAK1 抗体 (B-3) HRP

sc-376996 HRP
200 µg/ml
$316.00

JAK1 抗体 (B-3) FITC

sc-376996 FITC
200 µg/ml
$330.00

JAK1 抗体 (B-3) PE

sc-376996 PE
200 µg/ml
$343.00

JAK1 抗体 (B-3) Alexa Fluor® 488

sc-376996 AF488
200 µg/ml
$357.00

JAK1 抗体 (B-3) Alexa Fluor® 546

sc-376996 AF546
200 µg/ml
$357.00

JAK1 抗体 (B-3) Alexa Fluor® 594

sc-376996 AF594
200 µg/ml
$357.00

JAK1 抗体 (B-3) Alexa Fluor® 647

sc-376996 AF647
200 µg/ml
$357.00

JAK1 抗体 (B-3) Alexa Fluor® 680

sc-376996 AF680
200 µg/ml
$357.00

JAK1 抗体 (B-3) Alexa Fluor® 790

sc-376996 AF790
200 µg/ml
$357.00

Can JAK1 (B-3): sc-376996 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Cweed
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, JAK1 (B-3): sc-376996 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_28, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_376996, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 129ms
  • QUESTIONS, PRODUCT
Rated 1 out of 5 by from JAK1(B-3) antibody in rat cardiomyocytesvery weak signal in nuclei of cultures rat cardiomyocytes,
Date published: 2017-12-12
Rated 5 out of 5 by from goodLarge bands observed by Western Blot using Jurkat and MOLT-4 whole cell lysates. High background and some non-specific bands observed. -SCBT QC
Date published: 2017-09-07
Rated 5 out of 5 by from Excellent antibody for westernsprobed at 1/500X dilution for 90min and used in conjunction with the Kappa-binding-HRP as secondary and the blot turned out perfect. Excellent antibody for western blotting.
Date published: 2017-06-23
Rated 5 out of 5 by from excellent in WB!the four lines in the right is the sample transfected JAK1 vector in human HeLa cells and the left lines is the Endogenous JAK1 . the figure is detected just several seconds after WB autoradiography. so the antibody is so good in wb.
Date published: 2017-04-26
Rated 5 out of 5 by from Good for IP western blotI used this antibody for my IP WB on human samples, and it gave me strong band
Date published: 2017-03-30
Rated 5 out of 5 by from Produced superb immunofluorescence cytoplasmicProduced superb immunofluorescence cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-05-03
Rated 4 out of 5 by from Large bands observed by Western Blot usingLarge bands observed by Western Blot using Jurkat and MOLT-4 whole cell lysates. High background and some non-specific bands observed. -SCBT QC
Date published: 2015-02-02
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_376996, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 18ms
  • REVIEWS, PRODUCT
JAK1 抗体 (B-3) is rated 4.3 out of 5 by 7.
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_376996, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 109ms
  • REVIEWS, PRODUCT