Date published: 2025-9-6

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Huntingtin 抗体 (3H2242): sc-71287

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说明书
  • Huntingtin抗体(3H2242)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 免疫mouse物种的Huntingtin的氨基酸997-1276
  • 推荐用于 mouse, rat 和 human 来源的an epitope corresponding to the HDA region (amino acids 1171-1177) of Huntingtin WB, IP 和 IF检测
  • m-IgG Fc BP-HRP是Huntingtin Antibody (3H2242) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Huntingtin Antibody (3H2242) 搭配使用(请参阅下面的订购信息)。

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    亨廷顿蛋白是一种含有聚谷氨酰胺区的蛋白质。当谷氨酰胺重复次数超过35次时,该基因编码一种导致亨廷顿舞蹈症(HD)的亨廷顿蛋白。当聚谷氨酰胺区发生突变时,亨廷顿蛋白在细胞核内通过细胞特异性凋亡机制诱导神经退行性变。亨廷顿蛋白活性的丧失不太可能是HD的原因,有人提出,扩增的谷氨酰胺重复区域可能诱导突变蛋白与其他细胞蛋白之间的异常相互作用。亨廷顿蛋白与多种蛋白质相互作用,包括HAP1、甘油醛磷酸脱氢酶(GAPDH)和HIP1。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Huntingtin 抗体 (3H2242)

    sc-71287
    200 µg/ml
    $316.00

    Huntingtin (3H2242): m-IgG Fc BP-HRP 套装

    sc-539358
    200 µg Ab; 10 µg BP
    $354.00

    How much sample do you recommend loading on the gel for Western blot detection using Huntingtin (3H2242): sc-71287?

    Asked by: Randy McDonald
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 4 out of 5 by from Positive results in western blot with JurkatPositive results in western blot with Jurkat whole cell lysate. -SCBT QC
    Date published: 2013-04-14
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    Huntingtin 抗体 (3H2242) is rated 4.0 out of 5 by 1.
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