Date published: 2026-6-3

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HOOK2 Antibody (E-4): sc-137107

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Datasheets
  • HOOK2 Antibody (E-4) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against amino acids 157-236 mapping within an internal region of HOOK2 of human origin
  • recommended for detection of HOOK2 of human origin by WB, IP, IF and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for HOOK2 Antibody (E-4). This work is in progress.
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    HOOK2 Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects HOOK2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HOOK2, also known as HK2, is a 719 amino acid protein that plays a crucial role in the spatial organization of membrane-trafficking systems by interacting with microtubules and various organelles. HOOK2′s unique structure, characterized by a central coiled-coil domain that facilitates homodimerization, allows for forming stable complexes essential for maintaining cellular organization and function. HOOK2 shows strong expression in the larynx and esophagus, and HOOK2′s localization to distinct subcellular structures—unlike HOOK3, which is found in the Golgi apparatus—suggests a specialized role in these tissues. HOOK2 has been implicated in potential tumorigenic processes, as HOOK2 may associate with proteins such as SURF1 and Zic2, which are considered potential esophageal cancer tumor antigens. anti-HOOK2 antibody (E-4) effectively detects HOOK2 across various applications, making anti-HOOK2 antibody (E-4) an invaluable tool for researchers studying HOOK2′s function and implications in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    HOOK2 Antibody (E-4)

    sc-137107
    200 µg/ml
    $322.00

    How much sample do you recommend loading on the gel for Western blot detection using HOOK2 (E-4): sc-137107?

    Asked by: Dr Ninau Qelp
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Good Western Blot data of HOOK2 expression in nonGood Western Blot data of HOOK2 expression in non-transfected and human HOOK2 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-06-19
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    HOOK2 Antibody (E-4) is rated 5.0 out of 5 by 1.
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