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HOOK2 Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects HOOK2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HOOK2, also known as HK2, is a 719 amino acid protein that plays a crucial role in the spatial organization of membrane-trafficking systems by interacting with microtubules and various organelles. HOOK2′s unique structure, characterized by a central coiled-coil domain that facilitates homodimerization, allows for forming stable complexes essential for maintaining cellular organization and function. HOOK2 shows strong expression in the larynx and esophagus, and HOOK2′s localization to distinct subcellular structures—unlike HOOK3, which is found in the Golgi apparatus—suggests a specialized role in these tissues. HOOK2 has been implicated in potential tumorigenic processes, as HOOK2 may associate with proteins such as SURF1 and Zic2, which are considered potential esophageal cancer tumor antigens. anti-HOOK2 antibody (E-4) effectively detects HOOK2 across various applications, making anti-HOOK2 antibody (E-4) an invaluable tool for researchers studying HOOK2′s function and implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HOOK2 Antibody (E-4) | sc-137107 | 200 µg/ml | $322.00 |