Date published: 2025-9-9

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Hog1 抗体 (F-9): sc-365609

5.0(1)
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说明书
  • Hog1抗体(F-9)是小鼠单克隆IgM (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于Saccharomyces cerevisiae物种的Hog1的C-terminus附近的氨基酸389-421之间
  • 推荐用于 y 来源的Hog1 WB, IP, IF 和 ELISA检测
  • 目前,我们还没有完成Hog1 抗体 (F-9)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    酵母细胞通过MAP激酶级联反应调节其内部渗透压以应对环境。MAP激酶级联反应将细胞外信号传递到细胞质或细胞核,是信号转导的重要分支。这些级联反应的核心由一个MAP激酶(丝裂原活化蛋白激酶,也称为ERK,用于细胞外调节蛋白激酶)和一个或多个上游调节激酶(MAPKK或MEK,用于MAP/ERK激酶)组成。高外部渗透压导致MAPKK Pbs2的激活,从而激活MAP激酶Hog1。Hog1(也称为Ssk3)被认为可以激活转录因子,从而上调渗透调节蛋白的产生。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Hog1 抗体 (F-9) 参考文献:

    1. Rck2激酶是渗透应激激活的细胞分裂原活化蛋白激酶Hog1的底物。  |  Bilsland-Marchesan, E., et al. 2000. Mol Cell Biol. 20: 3887-95. PMID: 10805732
    2. MAPK Hog1招募Rpd3组蛋白去乙酰化酶来激活渗透反应基因。  |  De Nadal, E., et al. 2004. Nature. 427: 370-4. PMID: 14737171
    3. Hog1通过双重靶向Sic1来介导G1期细胞周期停滞。  |  Escoté, X., et al. 2004. Nat Cell Biol. 6: 997-1002. PMID: 15448699
    4. 更紧密的αC-螺旋-αL16-螺旋相互作用似乎使p38α不易通过自磷酸化激活,而Hog1则不然。  |  Tesker, M., et al. 2016. Biosci Rep. 36: PMID: 26987986
    5. 在真菌病原体中,应激诱导的核积累对于Hog1依赖性基因表达和毒力是必需的。  |  Day, AM., et al. 2017. Sci Rep. 7: 14340. PMID: 29085028
    6. MAP激酶HOG1通过促进多不饱和脂肪酸和甘油的生物合成来控制Rhodosporidium kratochvilovae的冷适应。  |  Chen, W., et al. 2022. Curr Microbiol. 79: 253. PMID: 35834133
    7. 根毛菌(Rhizophagus irregularis)中HOG1-MAPK级联基因的宿主和病毒诱导基因沉默抑制了菌根的发育,降低了植物对干旱胁迫的抵抗力。  |  Wang, S., et al. 2023. Plant Biotechnol J. 21: 866-883. PMID: 36609693
    8. 白领1通过调节镰刀菌中的HOG1通路来调节氧化敏感性和毒力。  |  Tang, Y., et al. 2023. Microbiol Spectr. 11: e0520622. PMID: 37195224
    9. 在葡萄孢属(Botryosphaeria dothidea)中,有丝分裂原活化蛋白激酶Hog1调节真菌发育、致病性和应激反应。  |  Zhang, Y., et al. 2024. Phytopathology. 114: 725-731. PMID: 37889135
    10. 在热应激期间,C. neoformans在缺乏Hog1/p38信号的情况下,Gcn2可恢复重编程。  |  Goich, D., et al. 2024. mBio. e0176224. PMID: 39670714

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Hog1 抗体 (F-9)

    sc-365609
    200 µg/ml
    $316.00

    Hog1 (F-9) 中和勝肽

    sc-365609 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365609 P appropriate for?

    Asked by: Germaine
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27

    Dear Madam/Mr, I am a postdoctor in Bath University UK, I trid to use your sc-365609 to detect ScHog1 but it does not work. But your sc-9079 could detect the ScHog1 from the same sample. Any ideas? Because I have to use the sc-365609

    Asked by: Kangzhen
    Thank you for your product review. We are sorry to hear that this antibody did not perform for you as expected. We want you to be successful in your research. Santa Cruz Biotechnology does warrant our antibodies for one year from the date of purchase. Please contact our Technical Service Department (europe@scbt.com). We are happy to help you to troubleshoot the experiment.
    Answered by: Technical Support Europe
    Date published: 2017-01-13
    • y_2025, m_8, d_27, h_5CST
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    Rated 5 out of 5 by from Nice Western blot data of yeast recombinantNice Western blot data of yeast recombinant Hog1 fusion protein. -SCBT QC
    Date published: 2013-11-20
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    Hog1 抗体 (F-9) is rated 5.0 out of 5 by 1.
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