Date published: 2025-9-11

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Hep B cAg 抗体 (1-5): sc-52406

4.5(2)
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说明书
  • Hep B cAg抗体(1-5)是小鼠单克隆IgG2a κ, 在6篇文献中引用,规格为200 µg/ml
  • 针对Hep B cAg
  • 推荐用于 Hep B 来源的an epitope corresponding to amino acids 74-80 of the core antigen WB, IP, IF, FCM 和 ELISA检测; 可能与 denatured Hep B cAg产生交联反应
  • 还可偶联FITC 用于IF, IHC(P) 和FCM
  • 看 Hep B cAg (C1-5): sc-23945,可查看有标记的 Hep B cAg 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Hep B cAg Antibody (1-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Hep B cAg Antibody (1-5) 打包提供(请参阅下面的订购信息)。

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関連項目

乙型肝炎病毒(Hepatitis B)是肝炎病毒家族的成员之一,它会导致肝炎、呕吐、黄疸,有时甚至会致死。乙型肝炎病毒是少数几种使用逆转录来复制基因组的非逆转录病毒之一。乙型肝炎病毒由三种主要抗原组成,分别是表面抗原(Hep B sAg)、包膜糖蛋白,在感染乙型肝炎病毒的个体血清中以膜状聚集物的形式存在;e抗原(Hep B eAg),通常与病毒复制率较高有关;以及核心抗原(Hep B cAg),它包裹着病毒基因组,构成了病毒蛋白头壳的组装和非组装变体。Hep B cAg和Hep B eAg主要用于乙型肝炎病毒的诊断,而Hep B sAg则主要用于疫苗的预防。乙型肝炎病毒抗原主要在肝脏中表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Hep B cAg 抗体 (1-5) 参考文献:

  1. 乙肝病毒核心抗原作为免疫原性肽的载体。  |  Murray, K. and Shiau, AL. 1999. Biol Chem. 380: 277-83. PMID: 10223329
  2. 乙肝病毒核心抗原决定了病毒在C57BL/6小鼠模型中的持久性。  |  Lin, YJ., et al. 2010. Proc Natl Acad Sci U S A. 107: 9340-5. PMID: 20439715
  3. 针对乙型肝炎e抗原和乙型肝炎核心抗原的单克隆抗体。  |  Sogut, I., et al. 2011. Hybridoma (Larchmt). 30: 475-9. PMID: 22008076
  4. 乙型肝炎病毒核衣壳,而不是游离的核心抗原,控制小鼠的病毒清除。  |  Lin, YJ., et al. 2012. J Virol. 86: 9266-73. PMID: 22718814
  5. 编码乙肝核心抗原的合成DNA免疫原可促进肝脏免疫反应。  |  Obeng-Adjei, N., et al. 2012. Cancer Gene Ther. 19: 779-87. PMID: 23037809
  6. 乙肝核心抗原的串联融合使得细菌和植物中类似病毒颗粒的组装能力增强,从而能够容纳外来蛋白。  |  Peyret, H., et al. 2015. PLoS One. 10: e0120751. PMID: 25830365
  7. 外周血单核细胞中乙肝核心抗原含量与HBV病毒载量的相关性。  |  Peng, Y., et al. 2016. Diagn Microbiol Infect Dis. 85: 154-8. PMID: 26680298
  8. 植物表达的乙型肝炎核心抗原病毒样颗粒:模拟和猪胃肠道液中稳定性的表征和调查。  |  Berardi, A., et al. 2017. Int J Pharm. 522: 147-156. PMID: 28263835
  9. 金纳米粒子修饰的还原氧化石墨烯靶向抗乙肝病毒核心抗原。  |  Abd Muain, MF., et al. 2018. Bioelectrochemistry. 122: 199-205. PMID: 29660648
  10. 志愿者血液中乙肝核心抗原抗体与逆转录病毒感染之间的关系。  |  Korelitz, JJ., et al. 1996. Transfusion. 36: 232-7. PMID: 8604508

订购信息

产品名称产品编号规格价格数量收藏夹

Hep B cAg 抗体 (1-5)

sc-52406
200 µg/ml
$316.00

Hep B cAg (1-5): m-IgG Fc BP-HRP 套装

sc-536855
200 µg Ab; 10 µg BP
$354.00

Hep B cAg (1-5): m-IgGκ BP-HRP 套装

sc-534022
200 µg Ab; 40 µg BP
$354.00

Hep B cAg (1-5): m-IgG2a BP-HRP 套装

sc-547884
200 µg Ab; 10 µg BP
$354.00

Hep B cAg 抗体 (1-5) FITC

sc-52406 FITC
200 µg/ml
$330.00

What's the difference between this antibody and the C1-5 antibody?

Asked by: Taha
Thank you for your question. These are both monoclonal antibodies that target the same Hep cAg protein. The exact epitopes have not been mapped. Please contact Technical Service if you have any further questions.
Answered by: Technical Support
Date published: 2019-02-01

Can Hep B cAg (1-5): sc-52406 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: jenniferc
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Hep B cAg (1-5): sc-52406 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Nice western blot stainingWe used this antibody for western blot staining and got a nice western blot at the correct molecular weight
Date published: 2017-01-27
Rated 4 out of 5 by from Publishable WB and ELISA using human HepG2Publishable WB and ELISA using human HepG2 and Hek293 - SCBT Publication Review
Date published: 2013-06-23
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Hep B cAg 抗体 (1-5) is rated 4.5 out of 5 by 2.
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