glypican-1 Antibody (4D1): sc-101827
- glypican-1 Antibody (4D1) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- raised against full length glypican-1 of human origin
- Anti-glypican-1 Antibody (4D1) is recommended for detection of glypican-1 of mouse, rat and human origin by WB, IP and IF
- Anti-glypican-1 Antibody (4D1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for glypican-1 Antibody (4D1). This work is in progress.
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SEE ALSO...
glypican-1 Antibody (4D1) is a mouse monoclonal IgG1 kappa light chain antibody that detects glypican-1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). anti-glypican-1 antibody (4D1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Glypican-1 (GPC1) is a crucial member of the glycosylphosphatidylinositol-anchored cell surface heparan sulfate proteoglycans, playing a significant role in cell adhesion, migration, and modulation of growth factor activities. GPC1 is located on the cell surface, where GPC1 interacts with several fibroblast growth factors (FGFs), including FGF-1, FGF-2, and FGF-7, thereby influencing cellular responses to these growth factors. GPC1 presence on marrow stromal cells is particularly important as GPC1 may facilitate maintenance and development of hematopoietic stem and progenitor cells. GPC1 acts as an extracellular chaperone for vascular endothelial growth factor 165 (VEGF165), enhancing receptor binding ability after oxidative stress. In pancreatic cancer, GPC1 is overexpressed compared to normal pancreatic cells, suggesting GPC1 involvement in tumor response to mitogenic stimuli such as FGF-2. The gene encoding human GPC1 is located on chromosome 2q37.3, highlighting genetic significance in various biological processes and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
glypican-1 Antibody (4D1) | sc-101827 | 200 µg/ml | $322.00 | |||
glypican-1 Antibody (4D1) AC | sc-101827 AC | 500 µg/ml, 25% agarose | $424.00 | |||
glypican-1 Antibody (4D1) HRP | sc-101827 HRP | 200 µg/ml | $322.00 | |||
glypican-1 Antibody (4D1) FITC | sc-101827 FITC | 200 µg/ml | $336.00 | |||
glypican-1 Antibody (4D1) PE | sc-101827 PE | 200 µg/ml | $349.00 | |||
glypican-1 Antibody (4D1) Alexa Fluor® 488 | sc-101827 AF488 | 200 µg/ml | $364.00 | |||
glypican-1 Antibody (4D1) Alexa Fluor® 546 | sc-101827 AF546 | 200 µg/ml | $364.00 | |||
glypican-1 Antibody (4D1) Alexa Fluor® 594 | sc-101827 AF594 | 200 µg/ml | $364.00 | |||
glypican-1 Antibody (4D1) Alexa Fluor® 647 | sc-101827 AF647 | 200 µg/ml | $364.00 | |||
glypican-1 Antibody (4D1) Alexa Fluor® 680 | sc-101827 AF680 | 200 µg/ml | $364.00 | |||
glypican-1 Antibody (4D1) Alexa Fluor® 790 | sc-101827 AF790 | 200 µg/ml | $364.00 |