Glucose Transporter Glut3 Antibody (B-6): sc-74497

Glut3 Antibody (B-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Glut3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Glut3 antibody (B-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Glut3 plays a crucial role in glucose metabolism, particularly in the brain, where Glut3 facilitates glucose uptake as the primary energy source for neurons. Glut3 expression remains particularly high in neuronal tissues, ensuring efficient glucose absorption even under low blood sugar conditions. This characteristic maintains brain health and function, especially during periods of fasting or intense neuronal activity. Glut3′s ability to transport glucose across the blood-brain barrier further underscores Glut3′s importance in neuroenergetics and overall metabolic homeostasis.

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Glucose Transporter Glut3 Antibody (B-6) References:

1. GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies.  |  Dai, W., et al. 2020. Signal Transduct Target Ther. 5: 177. PMID: 32873793
2. GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing.  |  Yu, DM., et al. 2023. J Clin Invest. 133: PMID: 37721853
3. GLUT3 regulates alternative macrophage signaling through a glucose transport-independent role.  |  Zhang, P., et al. 2023. J Clin Invest. 133: PMID: 37909335
4. Glucose transporter 3 (GLUT3) promotes lactylation modifications by regulating lactate dehydrogenase A (LDHA) in gastric cancer.  |  Yang, H., et al. 2023. Cancer Cell Int. 23: 303. PMID: 38041125
5. LPCAT1 Facilitates Keratinocyte Hyperproliferation and Skin Inflammation in Psoriasis by Regulating GLUT3.  |  Huang, Y., et al. 2024. J Invest Dermatol. 144: 1479-1490.e14. PMID: 38246582
6. Tumor-associated macrophages drive glycolysis through the IL-8/STAT3/GLUT3 signaling pathway in pancreatic cancer progression.  |  Zhong, Z., et al. 2024. Cancer Lett. 588: 216784. PMID: 38458594
7. GLUT3-mediated cigarette smoke-induced epithelial-mesenchymal transition in chronic obstructive pulmonary disease through the NF-kB/ZEB1 pathway.  |  Ding, Y., et al. 2024. Respir Res. 25: 158. PMID: 38594707
8. SIRT7 knockdown promotes gemcitabine sensitivity of pancreatic cancer cell via upregulation of GLUT3 expression.  |  Chen, K., et al. 2024. Cancer Lett. 598: 217109. PMID: 39002692
9. Neurodevelopment Is Dependent on Maternal Diet: Placenta and Brain Glucose Transporters GLUT1 and GLUT3.  |  Daida, T., et al. 2024. Nutrients. 16: PMID: 39064806
10. Glut3 promotes cellular O-GlcNAcylation as a distinctive tumor-supportive feature in Treg cells.  |  Sharma, A., et al. 2024. Cell Mol Immunol. 21: 1474-1490. PMID: 39468304

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Glucose Transporter Glut3 Antibody (B-6) has 28 citations in a variety of scientific publications.

Primary antibodies like Anti-Glucose Transporter Glut3 Antibody (B-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Glucose Transporter Glut3 Antibody (B-6) Specifications

Alternate Product Name: Glut3

Product Clone Name: B-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 216-265

Epitope Target: Glut3

Epitope Species: human

Product Reactivity/Detection: Glut3

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 28 citations in various scientific publications

Available Conjugates/Forms for Glucose Transporter Glut3 Antibody (B-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Glucose Transporter Glut3 antibody is Glucose Transporter Glut3 Antibody (G-5): sc-74399.