Date published: 2025-9-7

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Fgl2 抗体 (4H5): sc-100276

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说明书
  • Fgl2 抗体 4H5 是小鼠单克隆 IgG2a κ,Fgl2抗体, 在8篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组Fgl2
  • 推荐用于 mouse, rat 和 human 来源的Fibrinogen-like protein 2 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取Fgl2 (4H5): sc-100276免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG2a BP-HRP 是 Fgl2 抗体 (4H5) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Fgl2 抗体 (4H5) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Fgl2抗体(4H5)是一种IgG2a κ型小鼠单克隆Fgl2抗体(也称为Fgl2抗体),可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学(IHC(P))和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人源的Fgl2蛋白。Fgl2抗体(4H5)为非偶联的抗Fgl2抗体。纤维蛋白原样蛋白2(Fgl2),也称为纤维白细胞介素,由T细胞分泌,参与血栓形成起关键作用的疾病,如病毒引起的暴发性肝炎、胎儿丢失综合征和异种移植排斥反应。Fgl2在细胞毒性T细胞中呈组成性表达,对T细胞增殖和树突状细胞成熟具有免疫抑制作用。Fgl2是一种丝氨酸蛋白酶,可直接将凝血酶原裂解为凝血酶。Fgl2在病毒引起的肝炎和Th1细胞因子引起的胎儿丢失综合征等疾病的发病中起作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Fgl2 抗体 (4H5) 参考文献:

  1. 鼠肝炎病毒 3 型的核壳蛋白诱导新型 fgl2 凝血酶原基因的转录。  |  Ning, Q., et al. 1999. J Biol Chem. 274: 9930-6. PMID: 10187767
  2. FGL2 的基因组特征, 定域和功能表达,FGL2 是编码纤维蛋白素的人类基因:一种新型的人类促凝血剂。  |  Yuwaraj, S., et al. 2001. Genomics. 71: 330-8. PMID: 11170750
  3. 毒性小鼠肝炎病毒核壳蛋白对凝血酶原酶fgl2的诱导依赖于宿主肝核因子-4α。  |  Ning, Q., et al. 2003. J Biol Chem. 278: 15541-9. PMID: 12594208
  4. 可溶性纤维蛋白原样蛋白 2/纤维白蛋白具有免疫抑制特性:抑制 T 细胞增殖和骨髓树突状细胞成熟。  |  Chan, CW., et al. 2003. J Immunol. 170: 4036-44. PMID: 12682232
  5. 在急性血管异种移植排斥反应中,内皮诱导的fgl2有助于血栓形成。  |  Ghanekar, A., et al. 2004. J Immunol. 172: 5693-701. PMID: 15100314
  6. 仓鼠附睾上皮细胞表达和分泌纤维蛋白原相关蛋白 fgl2 的区域特异性及其在处理缺陷精子中的作用。  |  Olson, GE., et al. 2004. J Biol Chem. 279: 51266-74. PMID: 15377663

订购信息

产品名称产品编号规格价格数量收藏夹

Fgl2 抗体 (4H5)

sc-100276
100 µg/ml
$333.00

Fgl2 (4H5): m-IgG Fc BP-HRP 套装

sc-539679
100 µg Ab; 10 µg BP
$354.00

Fgl2 (4H5): m-IgG2a BP-HRP 套装

sc-546748
100 µg Ab; 10 µg BP
$354.00

How would you recommend using this antibody for flow cytometry? What concentration and whether the sample should be fixed or not?

Asked by: MaryamGH
Thank you for your question. We do not currently recommend this antibody for flow cytometry (FCM) because we have not tested the antibody in that application. However, we are aware of one product citation for FCM. Please refer to PMID: 29109438 for additional information.
Answered by: Technical Support
Date published: 2019-06-16

 Can sc-100276: Fgl2 (4H5) be stored at -20℃?

Asked by: KOBE
Thank you for your question. No, due to the buffer composition containing gelatin, it is not appropriate to store the antibodies at -20ºC, doing so will void the warranty and cause the reactivity to decline. The antibody is stable and should be stored at 4ºC.
Answered by: Technical Service
Date published: 2017-04-24

Can sc-100276: Fgl2 (4H5) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: jerojero
Thank you for your question. Yes, sc-100276: Fgl2 (4H5) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Great specificity for Fgl2 in Western BlotAntibody detects over-expressed human Fgl2 in transfected lysates sc-115132 and sc-158505 and endogenous Fgl2 in several cell lines. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Produced superb immunoperoxidase cytoplasmicProduced superb immunoperoxidase cytoplasmic staining in formalin-fixed, paraffin-embedded human stomach tissue. -SCBT QC
Date published: 2015-04-16
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Fgl2 抗体 (4H5) is rated 5.0 out of 5 by 3.
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