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Cytokeratin 4 Antibody (0.N.344): sc-70920

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Datasheets
  • Cytokeratin 4 Antibody (0.N.344) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
  • raised against cytokeratin preparation from esophagus cells of human origin
  • recommended for detection of Cytokeratin 4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM; also reactive with additional species, including and porcine, feline and canine
  • See pan-Cytokeratin (C11): sc-8018 for Cytokeratin 4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cytokeratin 4 Antibody (0.N.344). This work is in progress.
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Cytokeratin 4 Antibody (0.N.344) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 4 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Cytokeratin 4 is a member of the cytokeratin family, which plays a crucial role in maintaining the structural integrity of epithelial cells. Anti-Cytokeratin 4 antibody (0.N.344) targets proteins primarily located in the differentiated layers of the mucosal and esophageal epithelia, where Cytokeratin 4 contributes to the mechanical resilience of these tissues. Cytokeratin 4 is essential for the proper functioning of epithelial barriers, helping to protect against physical and chemical stressors. Additionally, Cytokeratin 4 expression, along with Cytokeratin 13, indicates the differentiation status of epithelial cells, making Cytokeratin 4 a valuable marker in the study of various epithelial malignancies. Cytokeratin 4 monoclonal antibody (0.N.344) enables researchers to gain insights into both normal physiology and disease states, enhancing our understanding of epithelial biology and pathology.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Cytokeratin 4 Antibody (0.N.344) References:

  1. Transcriptional gene expression profiles of oesophageal adenocarcinoma and normal oesophageal tissues.  |  Hourihan, RN., et al. 2003. Anticancer Res. 23: 161-5. PMID: 12680208
  2. Isolation and characterization of cultured human conjunctival goblet cells.  |  Shatos, MA., et al. 2003. Invest Ophthalmol Vis Sci. 44: 2477-86. PMID: 12766046
  3. Fascin and CK4 as biomarkers for esophageal squamous cell carcinoma.  |  Takikita, M., et al. 2011. Anticancer Res. 31: 945-52. PMID: 21498718
  4. Mass spectrometry-based salivary proteomics for the discovery of head and neck squamous cell carcinoma.  |  Jarai, T., et al. 2012. Pathol Oncol Res. 18: 623-8. PMID: 22350791
  5. Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)-based nanofibrous scaffolds to support functional esophageal epithelial cells towards engineering the esophagus.  |  Kuppan, P., et al. 2014. J Biomater Sci Polym Ed. 25: 574-93. PMID: 24502395
  6. In vitro evaluation of bi-layer silk fibroin scaffolds for gastrointestinal tissue engineering.  |  Franck, D., et al. 2014. J Tissue Eng. 5: 2041731414556849. PMID: 25396043
  7. Gene expression profiling to predict recurrence of advanced squamous cell carcinoma of the tongue: discovery and external validation.  |  Enokida, T., et al. 2017. Oncotarget. 8: 61786-61799. PMID: 28977904
  8. Evaluation of molecules or extracts modulating seborrhea and its consequences, using normal human culture of sebocytes and keratinocytes, skin explants models and in vivo methods: a case study.  |  Mondon, P., et al. 2017. J Cosmet Sci. 68: 183-194. PMID: 29619942
  9. Clinicocytopathological spectrum, including uncommon forms, of nine cases of chordomas with immunohistochemical results, including brachyury immunostaining: A single institutional experience.  |  Rekhi, B. and Karmarkar, S. 2019. Cytopathology. 30: 229-235. PMID: 30218622
  10. Topical treatment of ichthyoses and Darier's disease with 13-cis-retinoic acid. A clinical and immunohistochemical study.  |  Steijlen, PM., et al. 1993. Arch Dermatol Res. 285: 221-6. PMID: 7688204

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cytokeratin 4 Antibody (0.N.344)

sc-70920
100 µg/ml
$322.00

What is the total volume provided of Cytokeratin 4 (0.N.344): sc-70920 monoclonal antibody?

Asked by: Dr Ninau Qelp
Thank you for your question. Cytokeratin 4 (0.N.344): sc-70920 is provided as 100 µg in 1 ml total volume.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 3 out of 5 by LR from Works well for WB in HeLa samplesWorks well for WB in HeLa samples. -SCBT QC
Date published: 2015-02-10
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Cytokeratin 4 Antibody (0.N.344) is rated 3.0 out of 5 by 1.
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