Date published: 2025-9-5

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apoB 抗体 (C1.4): sc-13538

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说明书
  • apoB 抗体 C1.4 是小鼠单克隆 IgG1 κ,apoB抗体, 在25篇文献中引用,规格为200 µg/ml
  • apoB 抗体 (C1.4) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 apoB-100; 可能与 proteolytic degradation products, ApoB-75 and ApoB-26产生交联反应
  • 抗apoB抗体(C1.4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取apoB (C1.4): sc-13538免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP 是 apoB 抗体 (C1.4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与apoB 抗体 (C1.4) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGκ BP 偶联产品,请参阅我们的小鼠 IgG 结合蛋白完整列表。

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関連項目

apoB抗体(C1.4)是一种鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测人源性apoB蛋白。抗载脂蛋白B抗体(C1.4)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。载脂蛋白B在脂质代谢中起着至关重要的作用,是脂蛋白的主要结构成分,负责在血液中运输胆固醇和甘油三酯。这一功能对于维持脂质平衡和预防心血管疾病至关重要,因为脂蛋白水平失衡会导致动脉粥样硬化和其他代谢紊乱。值得注意的是,有两种同种异体的载脂蛋白B在血浆中循环:一种是在肝脏合成的载脂蛋白B-100,另一种是通过独特的转录后编辑过程在小肠产生的载脂蛋白B-48。人体能够从单个基因中产生这些不同形式的载脂蛋白B,这凸显了RNA编辑在调节脂质代谢中的重要性,也强调了载脂蛋白B单克隆抗体(C1.4)在心血管健康和代谢疾病研究中的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

apoB 抗体 (C1.4) 参考文献:

  1. 载脂蛋白 B mRNA 中编辑 C 下游的一个富含 AU 的序列元件(UUUN[A/U]U)是 Apobec-1 的高亲和力结合位点:Apobec-1 与 c-myc 3' 非翻译区中的该基团结合可增加 mRNA 的稳定性。  |  Anant, S. and Davidson, NO. 2000. Mol Cell Biol. 20: 1982-92. PMID: 10688645
  2. 过表达 APOBEC-1 可诱导细胞质载脂蛋白 B mRNA 的胞苷-尿苷编辑。  |  Yang, Y., et al. 2000. J Biol Chem. 275: 22663-9. PMID: 10833526
  3. 载脂蛋白 B mRNA 编辑是由多种载脂蛋白 B mRNA 编辑酶成分的协调调节介导的。  |  Chen, Z., et al. 2007. Am J Physiol Gastrointest Liver Physiol. 292: G53-65. PMID: 16920700
  4. 胆囊疾病患者的载脂蛋白 B (APOB) 基因多态性。  |  Kurzawski, M., et al. 2007. Arch Med Res. 38: 360-3. PMID: 17350490
  5. 了解载脂蛋白 B 的最新进展。  |  Young, SG. 1990. Circulation. 82: 1574-94. PMID: 1977530
  6. 通过双火箭免疫电泳法同时定量滤纸上血液中的脂蛋白 A-I 和 B。  |  Micic, S., et al. 1988. Clin Chem. 34: 2452-5. PMID: 3143508
  7. 人肝脂蛋白 B-100 cDNA:完整的核酸和衍生氨基酸序列。  |  Law, SW., et al. 1986. Proc Natl Acad Sci U S A. 83: 8142-6. PMID: 3464946
  8. 家族性低脂蛋白血症中的新型 APOB 突变。  |  Domenech, M., et al. 2022. J Clin Lipidol. 16: 28-32. PMID: 34852964
  9. 两种新的基于单克隆抗体的载脂蛋白 B 酶联检测法。  |  Young, SG., et al. 1986. Clin Chem. 32: 1484-90. PMID: 3524903
  10. 含载脂蛋白 B 的脂蛋白的生物合成和代谢。  |  Borén, J., et al. 2024. Annu Rev Nutr. 44: 179-204. PMID: 38635875
  11. 载脂蛋白B、非高密度脂蛋白胆固醇和甘油三酯之间的不协调:对心血管预防的影响。  |  Sniderman, AD., et al. 2024. Eur Heart J. 45: 2410-2418. PMID: 38700053
  12. 人类载脂蛋白 B:cDNA 克隆的鉴定和 mRNA 的特征。  |  Mehrabian, M., et al. 1985. Nucleic Acids Res. 13: 6937-53. PMID: 3903660

订购信息

产品名称产品编号规格价格数量收藏夹

apoB 抗体 (C1.4)

sc-13538
200 µg/ml
$316.00

apoB (C1.4): m-IgGκ BP-HRP 套装

sc-520627
200 µg Ab, 40 µg BP
$354.00

apoB 抗体 (C1.4) AC

sc-13538 AC
500 µg/ml, 25% agarose
$416.00

apoB 抗体 (C1.4) HRP

sc-13538 HRP
200 µg/ml
$316.00

apoB 抗体 (C1.4) FITC

sc-13538 FITC
200 µg/ml
$330.00

apoB 抗体 (C1.4) PE

sc-13538 PE
200 µg/ml
$343.00

apoB 抗体 (C1.4) Alexa Fluor® 488

sc-13538 AF488
200 µg/ml
$357.00

apoB 抗体 (C1.4) Alexa Fluor® 546

sc-13538 AF546
200 µg/ml
$357.00

apoB 抗体 (C1.4) Alexa Fluor® 594

sc-13538 AF594
200 µg/ml
$357.00

apoB 抗体 (C1.4) Alexa Fluor® 647

sc-13538 AF647
200 µg/ml
$357.00

apoB 抗体 (C1.4) Alexa Fluor® 680

sc-13538 AF680
200 µg/ml
$357.00

apoB 抗体 (C1.4) Alexa Fluor® 790

sc-13538 AF790
200 µg/ml
$357.00

Do you sell this antibody in any other species than mouse anti human? I am looking to order it in rabbit anti human to use a secondary of goat anti rabbit. Thank you very much.

Asked by: doryfishieharris
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-04-13

Does this antibody cross react with apoB-48?

Asked by: Stanley S
Thank you for your question. Please contact your local distributor or technical service for further assistance.
Answered by: Tech Service 1
Date published: 2021-01-21

I need to use an antibody to detect the protein in samples of canine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 7
Date published: 2017-02-09
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Rated 5 out of 5 by from Good AntibodyIt works perfectly in cell culture media. I got nice bands around 210 KDa. No background
Date published: 2019-02-27
Rated 3 out of 5 by from apoBWB:there are two bands and clear in liver tissue ,dilution 1:500.
Date published: 2017-08-09
Rated 4 out of 5 by from It workscan detect a strong band, use 1:500 dilution in HepG2 cells.
Date published: 2017-04-26
Rated 5 out of 5 by from Good staining!A good choice for IF and IHC as it provides strong and clear signals. It has been published with several times.
Date published: 2017-01-20
Rated 4 out of 5 by from Distinct band observed in Western blot analysisDistinct band observed in Western blot analysis of human recombinant apoB. -SCBT QC
Date published: 2015-05-18
Rated 4 out of 5 by from Published data using C1Published data using C1.4 for immunofluorescence and immunoblotting of Hep-G2 cells and lysates. -SCBT Publication Review
Date published: 2015-05-10
Rated 3 out of 5 by from Produced decent immunoperoxidase cytoplasmicProduced decent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human kidney tissue. -SCBT QC
Date published: 2015-04-05
Rated 4 out of 5 by from Worked well for WB and ELISAWorked well for WB and ELISA. -SCBT Publication Review
Date published: 2015-03-06
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apoB 抗体 (C1.4) is rated 4.0 out of 5 by 9.
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