Date published: 2025-9-9

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Aldose Reductase 抗体 (F-10): sc-133130

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说明书
  • Aldose Reductase抗体(F-10)是小鼠单克隆mouse IgG1 κ (kappa轻链),规格为200 µg/ml
  • 免疫human物种的代表全长Aldose Reductase的氨基酸1-316
  • 推荐用于 mouse, rat 和 human 来源的Aldose Reductase and Aldose Reductase-like proteins WB, IP, IF, IHC(P) 和 ELISA检测
  • m-IgGκ BP-HRP 是 Aldose Reductase 抗体 (F-10) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Aldose Reductase 抗体 (F-10) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGκ BP 偶联产品,请参阅我们的小鼠 IgG 结合蛋白完整列表。

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    醛糖还原酶(也称为ALR2)属于单体醛酮还原酶家族,存在NADPH依赖性。醛糖还原酶能催化各种醛的还原反应,并通过催化葡萄糖以醛形式存在的还原反应,生成对应的糖醇山梨糖醇,这与糖尿病并发症的发展过程相关。该途径对大多数组织中葡萄糖代谢过程作用不大,但在糖尿病高血糖症,细胞会经历非胰岛素依赖性葡萄糖摄取,积累大量的山梨糖醇。由此产生的细胞高渗应激可能会引起糖尿病并发症,如神经病变、视网膜病变和白内障。醛糖还原酶与人醛还原酶(称为ALR1)、牛前列腺素F合酶和欧洲林蛙蛋白rho-晶体蛋白非常相似。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Aldose Reductase 抗体 (F-10)

    sc-133130
    200 µg/ml
    $316.00

    Aldose Reductase (F-10): m-IgGκ BP-HRP 套装

    sc-551073
    200 µg Ab; 40 µg BP
    $354.00

    Can i use this antibody for immunoprecipitation? what is dilution range preferred for immunoprecipitation?

    Asked by: Anonymous
    Thank you for your question. Aldose Reductase Antibody (F-10): sc-133130 is recommended for detection of Aldose Reductase and Aldose Reductase-like proteins of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. For immunoprecipitation we recommend 1-2 µg per 100-500 µg of total protein (1 ml cell lysate).
    Answered by: Tech Support Europe
    Date published: 2021-02-11

    Can Aldose Reductase (F-10): sc-133130 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: jenniferc
    Thank you for your question. Yes, Aldose Reductase (F-10): sc-133130 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Great immunoperoxidase cytoplasmicGreat immunoperoxidase cytoplasmic, membrane and nuclear staining in formalin fixed, paraffin-embedded human adrenal gland tissue. -SCBT QC
    Date published: 2015-04-25
    Rated 5 out of 5 by from Satisfactory Western Blot data of AldoseSatisfactory Western Blot data of Aldose Reductase expression in Caki-1, JAR and KNRK whole cell lysates. -SCBT QC
    Date published: 2014-08-23
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    Aldose Reductase 抗体 (F-10) is rated 5.0 out of 5 by 2.
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