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ACSS1 Antibody (A-10) is a mouse monoclonal IgA antibody that detects ACSS1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACSS1, also known as acyl-CoA synthetase short-chain family member 1 or ACAS2L, is a 689 amino acid protein localized in the mitochondrial matrix, where ACSS1 plays a crucial role in cellular metabolism. ACSS1 is essential for converting acetate and coenzyme A into acetyl-CoA, a key substrate for the tricarboxylic acid cycle, which is vital for energy production in cardiac tissues. ACSS1′s ability to facilitate acetate oxidation underscores ACSS1′s importance in maintaining metabolic homeostasis, particularly in the heart, where energy demands are high. Additionally, ACSS1 is expressed in two alternatively spliced isoforms and is encoded by a gene located on chromosome 20, which harbors a significant portion of the human genome and is implicated in various genetic disorders. Anti-ACSS1 antibody (A-10) is an invaluable tool for researchers studying metabolic pathways and related diseases, providing insights into the functional dynamics of this critical enzyme.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACSS1 Antibody (A-10) | sc-373847 | 200 µg/ml | $322.00 | |||
ACSS1 (A-10) Neutralizing Peptide | sc-373847 P | 100 µg/0.5 ml | $69.00 |