Chromosome 18 open reading frame 21 (C18orf21), as denoted by its name, is a gene located on chromosome 18 in humans. The term "open reading frame" (ORF) refers to a sequence of DNA that has the potential to be translated into a protein. ORFs are identified by a start codon, usually AUG in eukaryotes, which signals the beginning of the protein-coding sequence, and a stop codon, which signals the end.C18orf21, like other open reading frames, would have been annotated based on genomic sequences that indicate the presence of a protein-coding region. However, the specific function of the protein encoded by C18orf21 may not be well characterized. Proteins encoded by ORFs can vary greatly in their function, ranging from enzymes involved in metabolic pathways to structural proteins, signaling molecules, or transcription factors that regulate gene expression.
These genes often require further experimental evidence to confirm their protein products and to understand their biological roles.If the protein product of C18orf21 has been characterized, it would be studied for aspects such as its amino acid sequence, three-dimensional structure, post-translational modifications, expression patterns, and interactions with other proteins. Insights into these areas could reveal its function in the cell, its involvement in specific biological processes, and its potential relevance to diseases or conditions associated with chromosome 18.
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产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
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Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
佛司可林可提高 cAMP 水平,从而激活 PKA。PKA 可能会使转录因子磷酸化,从而增强 C18orf21 的表达。 | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
维甲酸通过 RAR 受体发挥作用,RAR 受体可能与 C18orf21 启动子区域的维甲酸反应元件结合,导致其转录物被激活。 | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
作为一种 DNA 去甲基化剂,5-氮杂胞苷可导致基因启动子(可能包括 C18orf21)的低甲基化,从而增加其表达。 | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A 是一种 HDAC 抑制因子,可导致乙酰化程度更高(从而转录更活跃)的染色质状态,可能会增强 C18orf21 的表达。 | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG 可抑制 DNA 甲基转移酶,从而可能减少 C18orf21 启动子的甲基化并增强其表达。 | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
红豆杉能激活 Nrf2,从而上调与抗氧化反应元件相关的基因,如果 C18orf21 是这一途径的一部分,则可能包括 C18orf21。 | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
作为 PPARγ 激动剂,罗格列酮可能会反式激活 PPAR 反应基因,如果 C18orf21 具有 PPAR 反应元件,则可能包括 C18orf21。 | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
维生素 D3 可通过其受体 VDR 促进具有维生素 D 反应元件的基因的转录,其中可能包括 C18orf21。 | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
锂会影响 Wnt 信号转导,这可能会导致基因表达模式的改变,其中可能包括 C18orf21 的基因表达模式。 | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
TPA 可激活 PKC,而 PKC 可导致转录因子的激活,进而导致目的基因的表达,其中可能包括 C18orf21。 |