Date published: 2026-7-10

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NF2 Antibodies

Santa Cruz Biotechnology features a diverse variety of NF2 monoclonal antibodies for research focused on understanding the neurofibromatosis type 2 (NF2) gene and its associated protein, merlin. NF2 monoclonal antibodies are suitable for various applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The NF2 gene encodes merlin protein, which plays a crucial role in regulating cell growth and maintaining the structural integrity of cells. Mutations in the NF2 gene can lead to the development of tumors, particularly schwannomas and meningiomas, highlighting the significance of merlin in cancer research. Understanding merlin's function is essential for developing targeted therapies and improving patient outcomes. Research utilizing NF2 monoclonal antibodies has revealed important insights into cellular signaling pathways and tumor suppression mechanisms. Investigating merlin's interactions with other proteins has enhanced knowledge about cell adhesion and proliferation control. Current studies continue to uncover new aspects of NF2-related pathways and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of NF2-related diseases and developing innovative therapeutic approaches.

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NF2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Neurofibromin 2/NF2/Merlin Antibody (B-12)

sc-55575mouse IgG1 κ336-595 (h)WB, IP, IF, IHC(P), ELISAm, r, h
19
(12)

Neurofibromin 2/NF2/Merlin Antibody (E-2)

sc-55574mouse IgG2b κ336-595 (h)WB, IP, IF, ELISAm, r, h
4
(3)

NF2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Neurofibromin 2/NF2/Merlin siRNA (h)

sc-36052hGene SilencingN/A
3
(0)

Neurofibromin 2/NF2/Merlin shRNA Plasmid (h)

sc-36052-SHhGene SilencingPuromycin
3
(0)

Neurofibromin 2/NF2/Merlin shRNA (h) Lentiviral Particles

sc-36052-VhGene SilencingPuromycin
3
(0)

Neurofibromin 2/NF2/Merlin siRNA (m)

sc-36053mGene SilencingN/A
1
(0)

Neurofibromin 2/NF2/Merlin shRNA Plasmid (m)

sc-36053-SHmGene SilencingPuromycin
1
(0)

Neurofibromin 2/NF2/Merlin shRNA (m) Lentiviral Particles

sc-36053-VmGene SilencingPuromycin
1
(0)

NF2 CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Neurofibromin 2/NF2/Merlin CRISPR/Cas9 KO Plasmid (h)

sc-400504Gene Knockouth0
(0)

Neurofibromin 2/NF2/Merlin HDR Plasmid (h)

sc-400504-HDRHomology Directed Repairh0
(0)

Neurofibromin 2/NF2/Merlin CRISPR/Cas9 KO Plasmid (m)

sc-421862Gene Knockoutm0
(0)

Neurofibromin 2/NF2/Merlin HDR Plasmid (m)

sc-421862-HDRHomology Directed Repairm0
(0)

NF2 CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Neurofibromin 2/NF2/Merlin Double Nickase Plasmid (h)

sc-400504-NICGene Knockouth0
(0)

Neurofibromin 2/NF2/Merlin Double Nickase Plasmid (h2)

sc-400504-NIC-2Gene Knockouth0
(0)

Neurofibromin 2/NF2/Merlin Double Nickase Plasmid (m)

sc-421862-NICGene Knockoutm0
(0)

Neurofibromin 2/NF2/Merlin Double Nickase Plasmid (m2)

sc-421862-NIC-2Gene Knockoutm0
(0)

NF2 CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

Neurofibromin 2/NF2/Merlin CRISPR Activation Plasmid (h)

sc-400504-ACTGene Activationh0
(0)

Neurofibromin 2/NF2/Merlin CRISPR Activation Plasmid (h2)

sc-400504-ACT-2Gene Activationh0
(0)