Assuming "LIN-35" refers to a protein or gene that is integral to a particular biological process, activators of LIN-35 would be molecules that enhance its biological activity. These activators could potentially work by binding directly to the LIN-35 protein, inducing a conformational change that results in increased activity, or by facilitating its interaction with other proteins or substrates. The chemical structures of LIN-35 activators would likely be diverse, as they would need to possess specific characteristics that enable them to interact with distinct structural motifs or domains within LIN-35. These characteristics could include particular arrangements of atoms, charged groups, hydrophobic or hydrophilic elements, or even larger molecular frameworks for protein-protein interaction modulation.
In the realm of research, scientists investigating LIN-35 activators would employ a variety of techniques to understand the interaction between these molecules and the LIN-35 protein. Studies might include computational modeling to predict how these activators could bind to the protein and what effects they may exert on its structure and function. Experimental approaches would likely involve the use of in vitro assays to assess the biochemical consequences of activator binding, such as changes in the enzymatic activity of LIN-35 or alterations in its ability to interact with other cellular components. Advanced analytical techniques like mass spectrometry, circular dichroism, and fluorescence spectroscopy could provide insights into the binding dynamics and structural changes. Furthermore, if the precise structure of the LIN-35 protein were known, techniques such as X-ray crystallography or cryo-electron microscopy might be used to solve the structure of the protein in complex with activator molecules, giving a clear picture of the molecular interactions at play. This could elucidate the mechanism by which these activators enhance LIN-35 activity. Nonetheless, without concrete scientific evidence to define "LIN-35 Activators," this discussion remains purely theoretical and is not grounded in any known chemical classification.
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
羟基脲会诱导 DNA 损伤,并可能影响细胞周期调节蛋白,从而可能改变 LIN-35 的表达,这是应激反应的一部分。 | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
喜树碱通过抑制拓扑异构酶 I 诱导 DNA 损伤,这可能会导致 LIN-35 的表达发生变化,成为一种细胞反应。 | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
依托泊苷(Etoposide)通过抑制拓扑异构酶 II 导致 DNA 链断裂,可能会影响 DNA 损伤反应过程中 LIN-35 的表达。 | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Roscovitine 是一种细胞周期蛋白依赖性激酶抑制剂,可能会影响细胞周期调节因子,包括潜在的 LIN-35。 | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
Aphidicolin 是一种 DNA 聚合酶抑制剂,可能会导致 LIN-35 表达的改变,这是细胞周期检查点激活的一部分。 | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
紫杉醇能稳定微管并使细胞停止有丝分裂,在此过程中可能会影响 LIN-35 的表达。 | ||||||
Thymidine | 50-89-5 | sc-296542 sc-296542A sc-296542C sc-296542D sc-296542E sc-296542B | 1 g 5 g 100 g 250 g 1 kg 25 g | $48.00 $72.00 $265.00 $449.00 $1724.00 $112.00 | 16 | |
胸苷在高浓度使用时可导致细胞周期阻滞在 S 期,从而可能影响 LIN-35 的表达。 | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $92.00 $209.00 | 33 | |
甲氨蝶呤会抑制二氢叶酸还原酶,导致 S 期停滞,这可能会影响 LIN-35 等细胞周期调节因子的表达。 | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole 会破坏微管聚合,导致细胞周期停滞,从而影响 LIN-35 的表达水平。 | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
顺铂会形成 DNA 加合物,导致 DNA 损伤反应激活,这可能会影响 LIN-35 的表达,成为细胞反应的一部分。 |