Date published: 2026-5-17

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CES Substrates

Santa Cruz Biotechnology now offers a broad range of CES Substrates for use in various applications. CES, or Carboxylesterases, are a group of enzymes that play a significant role in the hydrolysis of ester and amide bonds, influencing the metabolism of a wide variety of endogenous and exogenous compounds. CES Substrates are crucial tools in scientific research, particularly in studies focusing on enzymatic activity, metabolism, and the detoxification processes within cells. Researchers use CES Substrates to investigate the specific reactions catalyzed by different carboxylesterases, which are vital for understanding how these enzymes contribute to the metabolism of lipids, xenobiotics, and other biochemical compounds. These substrates allow scientists to explore the kinetic properties and substrate specificities of CES enzymes, providing insights into their roles in metabolic pathways and their regulatory mechanisms. In addition, CES Substrates are widely used in studies of pharmacokinetics and toxicology to examine how carboxylesterases influence the breakdown and clearance of various chemicals and environmental toxins. The ability to measure CES activity using specific substrates enables researchers to better understand the enzyme's function in cellular homeostasis and its impact on the broader biochemical landscape. The availability of CES Substrates has greatly advanced research in areas such as biochemistry, molecular biology, and environmental science, where the precise understanding of metabolic processes is essential. These substrates are indispensable for studying the detailed mechanisms of ester hydrolysis and the role of carboxylesterases in maintaining cellular and organismal health. View detailed information on our available CES Substrates by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

3-Indoxyl butyrate

4346-15-0sc-283767
sc-283767A
500 mg
1 g
$112.00
$208.00
(0)

3-Indoxyl butyrate acts as a potent modulator of lipid metabolism, engaging in selective interactions with lipid-binding proteins. Its unique structure allows for enhanced solubility in biological membranes, promoting efficient cellular uptake. The compound exhibits distinct reaction kinetics, characterized by rapid hydrolysis under physiological conditions, which influences its bioavailability. Additionally, it can alter membrane fluidity, impacting cellular signaling and transport mechanisms.

5-Bromo-4-chloro-3-indoxyl palmitate

341972-98-3sc-284562
sc-284562A
50 mg
100 mg
$114.00
$218.00
(0)

5-Bromo-4-chloro-3-indoxyl palmitate is a versatile compound that exhibits unique reactivity as an acid halide, facilitating acylation reactions with various nucleophiles. Its halogenated structure enhances electrophilicity, promoting rapid reaction kinetics. The compound's hydrophobic palmitate tail contributes to its affinity for lipid environments, influencing membrane interactions and stability. This behavior can modulate enzymatic activity and affect cellular processes through altered lipid dynamics.

2-Naphthyl caprylate

10251-17-9sc-280282
sc-280282A
250 mg
500 mg
$216.00
$255.00
(0)

2-Naphthyl caprylate is a distinctive acid halide characterized by its aromatic naphthyl group, which enhances its electrophilic nature, allowing for efficient acylation with nucleophiles. The compound's long-chain caprylate moiety imparts significant lipophilicity, facilitating interactions with lipid membranes. This property can influence solubility and permeability, potentially affecting reaction pathways and kinetics in various chemical environments. Its unique structure allows for selective reactivity, making it a valuable tool in synthetic chemistry.

6-Chloro-3-indoxyl butyrate

159954-34-4sc-281480
sc-281480A
2 mg
5 mg
$168.00
$316.00
(0)

6-Chloro-3-indoxyl butyrate is an intriguing acid halide featuring a chloro-substituted indole structure, which contributes to its unique reactivity profile. The presence of the butyrate group enhances its ability to participate in acylation reactions, promoting rapid interactions with nucleophiles. This compound exhibits distinct solvation characteristics due to its polar and nonpolar regions, influencing its behavior in diverse chemical systems and potentially altering reaction mechanisms and rates.

6-Chloro-3-indoxyl palmitate

209347-96-6sc-281482
sc-281482A
10 mg
25 mg
$166.00
$310.00
(0)

6-Chloro-3-indoxyl palmitate is a distinctive acid halide characterized by its long-chain palmitate moiety, which significantly influences its lipophilicity and interaction with biological membranes. The chloro-indole framework facilitates unique electrophilic behavior, allowing for selective acylation with various nucleophiles. Its structural features promote specific molecular interactions, potentially leading to varied reaction kinetics and pathways in complex chemical environments.