These peptides are characterized by their structure, which typically includes a core of beta-sheet regions stabilized by disulfide bonds. This structure allows β-defensins to interact with and permeate the lipid membranes of pathogens, leading to their antimicrobial activity. Human β-defensins also possess immunomodulatory functions, such as recruiting immune cells to the site of infection and modulating cell signaling pathways involved in inflammation and immune responses.β-defensins are predominantly expressed in epithelial tissues that interface with the external environment, including the skin, respiratory, gastrointestinal, and urogenital tracts. This strategic expression pattern enables them to respond rapidly to microbial invasion at these critical barriers.
The expression of β-defensins can be induced by the presence of bacteria and other pathogens, as well as by cytokines and inflammatory mediators. This inducible nature allows for a rapid and localized increase in peptide concentration at infection sites, enhancing the body's ability to combat infectious agents.Should "β-defensin 125" be a member of this family, it would be expected to share these defining antimicrobial and immunomodulatory properties, contributing to the host's protective mechanisms against a wide array of pathogens.
产品名称 | CAS # | 产品编号 | 数量 | 价格 | 应用 | 排名 |
---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
维生素 D3 可通过维生素 D 受体(VDR)途径增强抗菌肽(包括 β-防御素)的表达。 | ||||||
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $63.00 $174.00 | ||
丁酸是肠道微生物群产生的一种短链脂肪酸,能上调肠道上皮细胞中防御素的表达。 | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $325.00 $632.00 $1428.00 $2450.00 $400.00 | 32 | |
它是维生素 D 的活性形式,在刺激免疫系统方面发挥作用,并能上调 β-防御素的表达。 | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
从维生素 A 中提取的维甲酸会影响免疫反应,并可能增强 β-防御素的表达。 | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
LPS 是革兰氏阴性细菌外膜的一种成分,可诱导 β防御素的表达,这是免疫反应的一部分。 | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
锌对免疫功能至关重要,已被证明能影响各种防御素的表达。 | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
白藜芦醇是一种多酚,可以调节免疫反应,并有可能上调β-防御素的表达。 | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
姜黄素具有抗炎特性,可能会影响包括β-防御素在内的抗菌肽的表达。 | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
绿茶中的 EGCG 具有抗炎特性,可能会影响 β-防御素的表达。 | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
乳铁蛋白是先天性免疫系统的一个组成部分,可以调节免疫反应,并可能调节β-防御素的表达。 |