Date published: 2026-7-10

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BACE2 Antibodies

Santa Cruz Biotechnology features a diverse variety of BACE2 monoclonal antibodies for research focused on understanding BACE2 protein function. BACE2 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).BACE2, or Beta-site APP Cleaving Enzyme 2, is a crucial enzyme involved in the processing of amyloid precursor protein (APP), which plays a significant role in Alzheimer's disease. By cleaving APP, BACE2 influences amyloid-beta peptide production, affecting neurodegenerative processes. Understanding BACE2 function is essential for developing therapeutic strategies aimed at mitigating the effects of Alzheimer's disease and other related disorders. Research utilizing BACE2 monoclonal antibodies has revealed important insights into APP processing pathways and potential therapeutic targets. Investigating BACE2 expression patterns helps identify its role in different tissues and cellular compartments. Studying BACE2 activity provides valuable information about its regulation and potential intervention points. Santa Cruz Biotechnology monoclonal antibodies for BACE2 support researchers worldwide in advancing our understanding of neurodegenerative diseases and developing new therapeutic approaches.

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BACE2 Antibodies

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BACE2 Antibody (H-3)

sc-271212mouse IgG2b κ429-518 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(4)

BACE2 Antibody (F-12)

sc-271286mouse IgG1 κ429-518 (h)WB, IP, IF, ELISAm, r, h
1
(1)

BACE2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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BACE2 siRNA (h)

sc-29776hGene SilencingN/A
2
(0)

BACE2 shRNA Plasmid (h)

sc-29776-SHhGene SilencingPuromycin
2
(0)

BACE2 shRNA (h) Lentiviral Particles

sc-29776-VhGene SilencingPuromycin
2
(0)

BACE2 siRNA (m)

sc-29777mGene SilencingN/A
1
(0)

BACE2 shRNA Plasmid (m)

sc-29777-SHmGene SilencingPuromycin
1
(0)

BACE2 shRNA (m) Lentiviral Particles

sc-29777-VmGene SilencingPuromycin
1
(0)

BACE2 CRISPR Knockout (KO) and HDR Plasmids

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BACE2 CRISPR/Cas9 KO Plasmid (h)

sc-403147Gene Knockouth0
(0)

BACE2 CRISPR/Cas9 KO Plasmid (m)

sc-425013Gene Knockoutm0
(0)

BACE2 CRISPR Activation Plasmids and Lentiviral Particles

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BACE2 CRISPR Activation Plasmid (h)

sc-403147-ACTGene Activationh0
(0)

BACE2 CRISPR Activation Plasmid (h2)

sc-403147-ACT-2Gene Activationh0
(0)