Date published: 2026-7-10

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AMPK Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of AMPK monoclonal antibodies for various research applications. AMPK monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). AMPK, or AMP-activated protein kinase, plays a crucial role in cellular energy homeostasis, acting as a key regulator of metabolism. AMPK is activated in response to low energy levels and helps to restore energy balance by promoting catabolic pathways while inhibiting anabolic processes. The study of AMPK is essential for understanding metabolic disorders, obesity, and the cellular response to stress. AMPK research has revealed significant insights into cellular metabolism and energy regulation pathways. AMPK signaling pathways are actively studied in cancer research, diabetes investigations, and cardiovascular disease research. Understanding AMPK activation mechanisms has opened new avenues for therapeutic interventions in metabolic diseases. Santa Cruz Biotechnology monoclonal antibodies for AMPK support researchers worldwide in advancing our understanding of cellular energy regulation and metabolic health.

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AMPK Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

AMPK alpha 1 Antibody (H-4)

sc-398861mouse IgG2b κ509-533 (h)WB, IP, IF, IHC(P), ELISAm, r, h
45
(13)

AMPK alpha 1 Antibody (71.54)

sc-130394mouse IgG2a κ451-551 (h)WB, IP, ELISAh
6
(2)

AMPK alpha 1/2 Antibody (D-6)

sc-74461mouse IgG2a κ251-550 (h)WB, IP, IF, IHC(P), ELISAm, r, h
146
(58)

AMPKβ1 Antibody (Z14)

sc-100357mouse IgG2a κ1-271 (h)WB, IP, IF, ELISAm, r, h
5
(7)

AMPKβ1 Antibody (1A7-E11-E9)

sc-517560mouse IgG(h)WB, IF, IHC(P)m, r, h

new

(0)

AMPKβ1 Antibody (142A2R)

sc-517606mouse IgG1 κ(h)WBm, r, h

new

(0)

AMPKβ2 Antibody (C-7)

sc-376752mouse IgG2a κ1-75 (h)WB, IP, IF, ELISAm, r, h
1
(5)

AMPKβ2 Antibody (362-7)

sc-100358mouse IgG2b κ1-273 (h)WB, IP, ELISAm, r, h

new

(2)

AMPKβ2 Antibody (F-8)

sc-376897mouse IgA1-75 (h)WB, IP, IF, ELISAm, r, h

new

(2)

AMPKγ2 Antibody (F-2)

sc-398804mouse IgG1 κ36-65 (h)WB, IP, IF, ELISAm, r, h

new

(5)

AMPK siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

AMPK alpha 1 siRNA (h)

sc-29673hGene SilencingN/A
77
(0)

AMPK alpha 1 siRNA (h2)

sc-44281hGene SilencingN/A
6
(0)

AMPK alpha 1 shRNA Plasmid (h)

sc-29673-SHhGene SilencingPuromycin
77
(0)

AMPK alpha 1 shRNA Plasmid (h2)

sc-44281-SHhGene SilencingPuromycin
6
(0)

AMPK alpha 1 shRNA (h) Lentiviral Particles

sc-29673-VhGene SilencingPuromycin
77
(0)

AMPK alpha 1 shRNA (h2) Lentiviral Particles

sc-44281-VhGene SilencingPuromycin
6
(0)

AMPK alpha 1 siRNA (m)

sc-29674mGene SilencingN/A
52
(0)

AMPK alpha 1 shRNA Plasmid (m)

sc-29674-SHmGene SilencingPuromycin
52
(0)

AMPK alpha 1 shRNA (m) Lentiviral Particles

sc-29674-VmGene SilencingPuromycin
52
(0)

AMPK alpha 1 siRNA (r)

sc-270142rGene SilencingN/A
32
(0)

AMPK alpha 1 shRNA Plasmid (r)

sc-270142-SHrGene SilencingPuromycin
32
(0)

AMPK alpha 1 shRNA (r) Lentiviral Particles

sc-270142-VrGene SilencingPuromycin
32
(0)

AMPK alpha 1 siRNA (bovine)

sc-270395bovineGene SilencingN/A
2
(0)

AMPK alpha 1 shRNA Plasmid (bovine)

sc-270395-SHbovineGene SilencingPuromycin
2
(0)

AMPK alpha 1 shRNA (bovine) Lentiviral Particles

sc-270395-VbovineGene SilencingPuromycin
2
(0)

AMPKβ1 siRNA (h)

sc-38925hGene SilencingN/A
5
(0)

AMPKβ1 shRNA Plasmid (h)

sc-38925-SHhGene SilencingPuromycin
5
(0)

AMPKβ1 shRNA (h) Lentiviral Particles

sc-38925-VhGene SilencingPuromycin
5
(0)

AMPKβ1 siRNA (m)

sc-38926mGene SilencingN/A0
(0)

AMPKβ1 shRNA Plasmid (m)

sc-38926-SHmGene SilencingPuromycin0
(0)

AMPKβ1 shRNA (m) Lentiviral Particles

sc-38926-VmGene SilencingPuromycin0
(0)

AMPKγ1 siRNA (h)

sc-38929hGene SilencingN/A
2
(0)

AMPKγ1 shRNA Plasmid (h)

sc-38929-SHhGene SilencingPuromycin
2
(0)

AMPKγ1 shRNA (h) Lentiviral Particles

sc-38929-VhGene SilencingPuromycin
2
(0)

AMPKγ1 siRNA (m)

sc-38930mGene SilencingN/A0
(0)

AMPKγ1 shRNA Plasmid (m)

sc-38930-SHmGene SilencingPuromycin0
(0)

AMPKγ1 shRNA (m) Lentiviral Particles

sc-38930-VmGene SilencingPuromycin0
(0)

AMPK alpha 2 siRNA (h)

sc-38923hGene SilencingN/A
22
(0)

AMPK alpha 2 shRNA Plasmid (h)

sc-38923-SHhGene SilencingPuromycin
22
(0)

AMPK alpha 2 shRNA (h) Lentiviral Particles

sc-38923-VhGene SilencingPuromycin
22
(0)

AMPK alpha 2 siRNA (m)

sc-38924mGene SilencingN/A
11
(0)

AMPK alpha 2 siRNA (m2)

sc-270315mGene SilencingN/A0
(0)

AMPK alpha 2 shRNA Plasmid (m)

sc-38924-SHmGene SilencingPuromycin
11
(0)

AMPK alpha 2 shRNA Plasmid (m2)

sc-270315-SHmGene SilencingPuromycin0
(0)

AMPK alpha 2 shRNA (m) Lentiviral Particles

sc-38924-VmGene SilencingPuromycin
11
(0)

AMPK alpha 2 shRNA (m2) Lentiviral Particles

sc-270315-VmGene SilencingPuromycin0
(0)

AMPK alpha 2 siRNA (r)

sc-155985rGene SilencingN/A
14
(0)

AMPK alpha 2 shRNA Plasmid (r)

sc-155985-SHrGene SilencingPuromycin
14
(0)

AMPK alpha 2 shRNA (r) Lentiviral Particles

sc-155985-VrGene SilencingPuromycin
14
(0)

AMPK alpha 2 siRNA (ovine)

sc-270396ovineGene SilencingN/A
1
(0)

AMPK alpha 2 shRNA Plasmid (ovine)

sc-270396-SHovineGene SilencingPuromycin
1
(0)

AMPK alpha 2 shRNA (ovine) Lentiviral Particles

sc-270396-VovineGene SilencingPuromycin
1
(0)

AMPKβ2 siRNA (h)

sc-38927hGene SilencingN/A
2
(0)

AMPKβ2 shRNA Plasmid (h)

sc-38927-SHhGene SilencingPuromycin
2
(0)

AMPKβ2 shRNA (h) Lentiviral Particles

sc-38927-VhGene SilencingPuromycin
2
(0)

AMPKβ2 siRNA (m)

sc-38928mGene SilencingN/A0
(0)

AMPKβ2 shRNA Plasmid (m)

sc-38928-SHmGene SilencingPuromycin0
(0)

AMPKβ2 shRNA (m) Lentiviral Particles

sc-38928-VmGene SilencingPuromycin0
(0)

AMPKγ2 siRNA (h)

sc-38931hGene SilencingN/A0
(0)

AMPKγ2 shRNA Plasmid (h)

sc-38931-SHhGene SilencingPuromycin0
(0)

AMPKγ2 shRNA (h) Lentiviral Particles

sc-38931-VhGene SilencingPuromycin0
(0)

AMPKγ2 siRNA (m)

sc-38932mGene SilencingN/A0
(0)

AMPKγ2 shRNA Plasmid (m)

sc-38932-SHmGene SilencingPuromycin0
(0)

AMPKγ2 shRNA (m) Lentiviral Particles

sc-38932-VmGene SilencingPuromycin0
(0)

AMPKγ3 siRNA (h)

sc-38933hGene SilencingN/A0
(0)

AMPKγ3 shRNA Plasmid (h)

sc-38933-SHhGene SilencingPuromycin0
(0)

AMPKγ3 shRNA (h) Lentiviral Particles

sc-38933-VhGene SilencingPuromycin0
(0)

AMPKγ3 siRNA (m)

sc-72114mGene SilencingN/A0
(0)

AMPKγ3 shRNA Plasmid (m)

sc-72114-SHmGene SilencingPuromycin0
(0)

AMPKγ3 shRNA (m) Lentiviral Particles

sc-72114-VmGene SilencingPuromycin0
(0)

AMPK alpha 1/2 siRNA (h)

sc-45312hGene SilencingN/A
175
(3)

AMPK alpha 1/2 shRNA Plasmid (h)

sc-45312-SHhGene SilencingPuromycin
175
(3)

AMPK alpha 1/2 shRNA (h) Lentiviral Particles

sc-45312-VhGene SilencingPuromycin
175
(3)

AMPK alpha 1/2 siRNA (m)

sc-45313mGene SilencingN/A
54
(0)

AMPK alpha 1/2 shRNA Plasmid (m)

sc-45313-SHmGene SilencingPuromycin
54
(0)

AMPK alpha 1/2 shRNA (m) Lentiviral Particles

sc-45313-VmGene SilencingPuromycin
54
(0)

AMPKγ1/2/3 siRNA (h)

sc-43613hGene SilencingN/A0
(0)

AMPKγ1/2/3 shRNA Plasmid (h)

sc-43613-SHhGene SilencingPuromycin0
(0)

AMPKγ1/2/3 shRNA (h) Lentiviral Particles

sc-43613-VhGene SilencingPuromycin0
(0)

AMPK CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

AMPK alpha 1 CRISPR/Cas9 KO Plasmid (h)

sc-400104Gene Knockouth0
(0)

AMPK alpha 1 HDR Plasmid (h)

sc-400104-HDRHomology Directed Repairh0
(0)

AMPK alpha 1 CRISPR/Cas9 KO Plasmid (m)

sc-430618Gene Knockoutm0
(0)

AMPK alpha 1 HDR Plasmid (m)

sc-430618-HDRHomology Directed Repairm0
(0)

AMPKβ1 CRISPR/Cas9 KO Plasmid (h)

sc-402952Gene Knockouth0
(0)

AMPKβ1 HDR Plasmid (h)

sc-402952-HDRHomology Directed Repairh0
(0)

AMPKβ1 CRISPR/Cas9 KO Plasmid (m2)

sc-422398-KO-2Gene Knockoutm0
(0)

AMPKβ1 HDR Plasmid (m2)

sc-422398-HDR-2Homology Directed Repairm0
(0)

AMPKγ1 CRISPR/Cas9 KO Plasmid (h2)

sc-418058-KO-2Gene Knockouth0
(0)

AMPKγ1 HDR Plasmid (h2)

sc-418058-HDR-2Homology Directed Repairh0
(0)

AMPK alpha 2 CRISPR/Cas9 KO Plasmid (h)

sc-400277Gene Knockouth0
(0)

AMPK alpha 2 HDR Plasmid (h)

sc-400277-HDRHomology Directed Repairh0
(0)

AMPK alpha 2 CRISPR/Cas9 KO Plasmid (m)

sc-430803Gene Knockoutm0
(0)

AMPK alpha 2 HDR Plasmid (m)

sc-430803-HDRHomology Directed Repairm0
(0)

AMPKβ2 CRISPR/Cas9 KO Plasmid (h)

sc-403537Gene Knockouth0
(0)

AMPKβ2 CRISPR/Cas9 KO Plasmid (m)

sc-430808Gene Knockoutm0
(0)

AMPKβ2 HDR Plasmid (m)

sc-430808-HDRHomology Directed Repairm0
(0)

AMPKγ2 CRISPR/Cas9 KO Plasmid (h)

sc-404970Gene Knockouth0
(0)

AMPKγ2 HDR Plasmid (h)

sc-404970-HDRHomology Directed Repairh0
(0)

AMPKγ2 CRISPR/Cas9 KO Plasmid (m)

sc-430810Gene Knockoutm0
(0)

AMPKγ2 HDR Plasmid (m)

sc-430810-HDRHomology Directed Repairm0
(0)

AMPKγ3 CRISPR/Cas9 KO Plasmid (m)

sc-433813Gene Knockoutm0
(0)

AMPKγ3 HDR Plasmid (m)

sc-433813-HDRHomology Directed Repairm0
(0)

AMPK CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

AMPK alpha 1 Double Nickase Plasmid (h)

sc-400104-NICGene Knockouth0
(0)

AMPK alpha 1 Double Nickase Plasmid (h2)

sc-400104-NIC-2Gene Knockouth0
(0)

AMPKβ1 Double Nickase Plasmid (h)

sc-402952-NICGene Knockouth0
(0)

AMPKβ1 Double Nickase Plasmid (h2)

sc-402952-NIC-2Gene Knockouth0
(0)

AMPKβ1 Double Nickase Plasmid (m)

sc-422398-NICGene Knockoutm0
(0)

AMPKβ1 Double Nickase Plasmid (m2)

sc-422398-NIC-2Gene Knockoutm0
(0)

AMPK alpha 2 Double Nickase Plasmid (h)

sc-400277-NICGene Knockouth0
(0)

AMPK alpha 2 Double Nickase Plasmid (h2)

sc-400277-NIC-2Gene Knockouth0
(0)

AMPK alpha 2 Double Nickase Plasmid (m)

sc-430803-NICGene Knockoutm0
(0)

AMPKβ2 Double Nickase Plasmid (h)

sc-403537-NICGene Knockouth0
(0)

AMPKβ2 Double Nickase Plasmid (h2)

sc-403537-NIC-2Gene Knockouth0
(0)

AMPK CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

AMPK alpha 1 CRISPR Activation Plasmid (h)

sc-400104-ACTGene Activationh0
(0)

AMPK alpha 1 Lentiviral Activation Particles (h)

sc-400104-LACGene Activationh0
(0)

AMPK alpha 1 CRISPR Activation Plasmid (m2)

sc-430618-ACT-2Gene Activationm0
(0)

AMPK alpha 1 Lentiviral Activation Particles (m2)

sc-430618-LAC-2Gene Activationm0
(0)

AMPKβ1 CRISPR Activation Plasmid (h)

sc-402952-ACTGene Activationh0
(0)

AMPKβ1 CRISPR Activation Plasmid (h2)

sc-402952-ACT-2Gene Activationh0
(0)

AMPKβ1 Lentiviral Activation Particles (h)

sc-402952-LACGene Activationh0
(0)

AMPKγ1 CRISPR Activation Plasmid (h)

sc-418058-ACTGene Activationh0
(0)

AMPKγ1 CRISPR Activation Plasmid (h2)

sc-418058-ACT-2Gene Activationh0
(0)

AMPKγ1 Lentiviral Activation Particles (h)

sc-418058-LACGene Activationh0
(0)

AMPK alpha 2 CRISPR Activation Plasmid (h)

sc-400277-ACTGene Activationh0
(0)

AMPK alpha 2 CRISPR Activation Plasmid (h2)

sc-400277-ACT-2Gene Activationh0
(0)

AMPK alpha 2 Lentiviral Activation Particles (h)

sc-400277-LACGene Activationh0
(0)

AMPKβ2 CRISPR Activation Plasmid (h)

sc-403537-ACTGene Activationh0
(0)

AMPKβ2 CRISPR Activation Plasmid (h2)

sc-403537-ACT-2Gene Activationh0
(0)

AMPKβ2 Lentiviral Activation Particles (h)

sc-403537-LACGene Activationh0
(0)

AMPKγ2 CRISPR Activation Plasmid (h)

sc-404970-ACTGene Activationh0
(0)

AMPKγ2 CRISPR Activation Plasmid (h2)

sc-404970-ACT-2Gene Activationh0
(0)

AMPKγ2 Lentiviral Activation Particles (h)

sc-404970-LACGene Activationh0
(0)

AMPKγ3 CRISPR Activation Plasmid (h)

sc-403280-ACTGene Activationh0
(0)

AMPKγ3 CRISPR Activation Plasmid (h2)

sc-403280-ACT-2Gene Activationh0
(0)