Date published: 2025-11-1

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LDLR Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of LDLR monoclonal antibodies for various research applications. LDLR monoclonal antibodies are optimized for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Low-Density Lipoprotein Receptor (LDLR) plays a critical role in lipid metabolism by mediating the endocytosis of cholesterol-rich lipoproteins, thereby regulating cholesterol levels in the bloodstream. Dysregulation of LDLR function is associated with hypercholesterolemia and cardiovascular diseases, making it a significant target for therapeutic interventions. Understanding LDLR's role in cellular processes is essential for advancing research in lipid metabolism and related disorders. LDLR monoclonal antibodies enable researchers to investigate cellular uptake mechanisms and track protein expression patterns across different tissue types. Studying LDLR activity provides insights into cholesterol homeostasis and potential therapeutic strategies for cardiovascular conditions. LDLR research using Santa Cruz Biotechnology monoclonal antibodies continues to advance our understanding of lipid metabolism and cardiovascular health, supporting breakthrough discoveries in the scientific community.

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LDLR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

LDLR Antibody (C7)

sc-18823mouse IgG2b κ(bovine)WB, IP, IF, IHC(P)m, r, h
62
(16)

LDLR Antibody (B-10)

sc-373831mouse IgG2b κ13-47 (h)WB, IP, IF, ELISAh

new

(2)

LDLR Antibody (F-7)

sc-373830mouse IgG2a κ13-47 (h)WB, IP, IF, ELISAh
6
(4)

LDLR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LDLR CRISPR/Cas9 KO Plasmid (h2)

sc-400645-KO-2hGene KnockoutGFP0
(1)

LDLR HDR Plasmid (h2)

sc-400645-HDR-2hHomology Directed RepairPuromycin0
(1)

LDLR Double Nickase Plasmid (h)

sc-400645-NIChGene KnockoutPuromycin0
(1)

LDLR Double Nickase Plasmid (h2)

sc-400645-NIC-2hGene KnockoutPuromycin0
(1)

LDLR CRISPR/Cas9 KO Plasmid (m)

sc-421408mGene KnockoutGFP
2
(0)

LDLR HDR Plasmid (m)

sc-421408-HDRmHomology Directed RepairPuromycin
2
(0)

LDLR Double Nickase Plasmid (m)

sc-421408-NICmGene KnockoutPuromycin
2
(0)

LDLR Double Nickase Plasmid (m2)

sc-421408-NIC-2mGene KnockoutPuromycin
2
(0)

LDLR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LDLR CRISPR Activation Plasmid (h)

sc-400645-ACThGene ActivationPuro, Blast, Hygro0
(1)

LDLR CRISPR Activation Plasmid (h2)

sc-400645-ACT-2hGene ActivationPuro, Blast, Hygro0
(1)

LDLR Lentiviral Activation Particles (h)

sc-400645-LAChGene ActivationPuro, Blast, Hygro0
(1)

LDLR Lentiviral Activation Particles (h2)

sc-400645-LAC-2hGene ActivationPuro, Blast, Hygro0
(1)

LDLR CRISPR Activation Plasmid (m)

sc-421408-ACTmGene ActivationPuro, Blast, Hygro
2
(0)

LDLR CRISPR Activation Plasmid (m2)

sc-421408-ACT-2mGene ActivationPuro, Blast, Hygro
2
(0)

LDLR Lentiviral Activation Particles (m)

sc-421408-LACmGene ActivationPuro, Blast, Hygro
2
(0)

LDLR Lentiviral Activation Particles (m2)

sc-421408-LAC-2mGene ActivationPuro, Blast, Hygro
2
(0)

LDLR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

LDLR siRNA (h)

sc-35802hGene SilencingN/A
4
(0)

LDLR shRNA Plasmid (h)

sc-35802-SHhGene SilencingPuromycin
4
(0)

LDLR shRNA (h) Lentiviral Particles

sc-35802-VhGene SilencingPuromycin
4
(0)

LDLR siRNA (m)

sc-35803mGene SilencingN/A
3
(0)

LDLR shRNA Plasmid (m)

sc-35803-SHmGene SilencingPuromycin
3
(0)

LDLR shRNA (m) Lentiviral Particles

sc-35803-VmGene SilencingPuromycin
3
(0)

LDLR siRNA (r)

sc-156112rGene SilencingN/A0
(0)

LDLR shRNA (r) Lentiviral Particles

sc-156112-VrGene SilencingPuromycin0
(0)

LDLR shRNA shRNA Plasmid (r)

sc-156112-SHrGene SilencingPuromycin0
(0)