Date published: 2025-10-8
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Dengue Virus Antibody (9.F.10): sc-70959

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Datasheets
  • Dengue Virus Antibody (9.F.10) is a mouse monoclonal IgG2a, cited in 5 publications, provided at 100 µg/ml
  • raised against Dengue Virus serotypes 1, 2, 3, and 4
  • recommended for detection of Dengue Virus 1, 2, 3 and 4 of Dengue Virus 1, 2, 3 and and 4 origin by WB, IF and IHC(P)
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Dengue Virus Antibody (9.F.10). This work is in progress.

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Description
Datasheets and Protocols
Research Information

SEE ALSO...

Additional Dengue Virus Antibodies including and Dengue Virus 2

Dengue Virus Antibody (9.F.10) is a mouse monoclonal IgG2a antibody that detects Dengue Virus across serotypes 1, 2, 3, and 4 through western blotting (WB), immunofluorescence (IF), and immunohistochemistry. Anti-Dengue Virus antibody (9.F.10) plays a crucial role in studying Dengue Virus, a member of the Flavivirus genus responsible for causing Dengue fever, a significant public health concern in tropical regions. The virus′s genome consists of a single-stranded positive-sense RNA that encodes three structural proteins—capsid, membrane, and envelope—as well as seven nonstructural proteins essential for viral replication and pathogenesis. The envelope protein facilitates fusion of viral and cellular membranes, enabling viral entry into host cells for replication. Understanding these proteins′ structure and function is vital for developing effective vaccines and therapeutic strategies against Dengue fever, and for elucidating viral infection and immune response mechanisms.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Dengue Virus Antibody (9.F.10) References:

  1. Neurological complications of dengue virus infection.  |  Carod-Artal, FJ., et al. 2013. Lancet Neurol. 12: 906-919. PMID: 23948177
  2. Dengue virus vaccine development.  |  Yauch, LE. and Shresta, S. 2014. Adv Virus Res. 88: 315-72. PMID: 24373316
  3. Pharmacological intervention for dengue virus infection.  |  Lai, JH., et al. 2017. Biochem Pharmacol. 129: 14-25. PMID: 28104437
  4. New insight on dengue virus-induced thrombocytopenia.  |  Goldthorpe, SC. and Conway, MJ. 2017. Virulence. 8: 1492-1493. PMID: 28829671
  5. Discovery of Dengue Virus Inhibitors.  |  Abdullah, AA., et al. 2020. Curr Med Chem. 27: 4945-5036. PMID: 30514185
  6. Dengue virus and the complement alternative pathway.  |  Carr, JM., et al. 2020. FEBS Lett. 594: 2543-2555. PMID: 31943152
  7. microRNAs, the Link Between Dengue Virus and the Host Genome.  |  Su, Y., et al. 2021. Front Microbiol. 12: 714409. PMID: 34456895
  8. Contribution of phylogenetics to understanding the evolution and epidemiology of dengue virus.  |  Yu, X. and Cheng, G. 2022. Animal Model Exp Med. 5: 410-417. PMID: 36245335
  9. Host immunity and vaccine development against Dengue virus.  |  Ma, E. and Cheng, G. 2022. Infect Med (Beijing). 1: 50-58. PMID: 38074980
  10. Cross Talk between MicroRNAs and Dengue Virus.  |  Macha, NO., et al. 2024. Am J Trop Med Hyg. 110: 856-867. PMID: 38579704

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dengue Virus Antibody (9.F.10)

sc-70959
100 µg/ml
$316.00

Which cell line was used to validate this antibody? Was there any unspecific band observed?

Asked by: Ankita v
Thank you for your question. Please contact your local distributor or technical service for further assistance.
Answered by: Tech Service 1
Date published: 2021-01-21

What is the epitope of this antibody? I know this question has been asked before but knowing the exact epitope is extremely important especially for researchers who mutate proteins. Without that information, the antibody is practically useless.

Asked by: CWOLLNER
Thank you for your question. We do know that this monoclonal antibody specifically recognizes Dengue envelope antigen (anti-E or envelope specific) for all four Dengue virus subgroups (1, 2, 3, 4). However, the exact epitope recognized has not been determined.
Answered by: Technical Support
Date published: 2020-07-16

I bought this antibody in October last year and it came with the secondary antibody conjugated with HRP so, I wonder if the Ab sc-70959 comes with the secondary antibody or if I need to buy the secondary separately?

Asked by: MAXIMPARIS2018
Thank your for your question. The sc-70959 can be used in combination with our mouse IgG kappa binding protein (m-IgGκ BP) conjugated to Horseradish Peroxidase (HRP) sc-516102. Please contact technical service if you need additional information.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-29

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with Dengue Virus Antibody (9.F.10): sc-70959?

Asked by: Trav11
We recommend using one of our our exclusive Mouse IgG Binding Proteins (m-IgGκ) conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 13
Date published: 2018-04-04

What is the recommended secondary reagent for Western blot?

Asked by: Trav11
Thank you for your question. We recommend using one of our exclusive Mouse IgG Binding Proteins as a secondary detection reagent, such as m-IgGκ BP-HRP: sc-516102, for Western blot. A complete list of all available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-8301 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Technical Service 11
Date published: 2017-01-16

Hello, I wanted to confirm about the exact target of this antibody as in what domain of the E protein is its target?

Asked by: Fareeha
Thank you for your inquiry. There is no additional information regarding the binding location or epitope of this Dengue Virus antibody, sc-70959.
Answered by: Technical Service
Date published: 2020-03-30
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Rated 5 out of 5 by from Smart choiceThis is a popular antibody for Dengue virus detection. Highly recommend for WB and IHC.
Date published: 2017-01-16
Rated 4 out of 5 by from This antibody was used in a publication forThis antibody was used in a publication for WB on mosquitoe brain, salivary glands, fat bodies, midguts, malpighian tubes, and ovaries - SCBT Publication Review
Date published: 2014-07-26
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Dengue Virus Antibody (9.F.10) is rated 4.5 out of 5 by 2.
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