Date published: 2025-10-17

1-800-457-3801

SCBT Portrait Logo
Seach Input

5 alpha-Reductase 1 Inhibitors

Santa Cruz Biotechnology now offers a broad range of 5 alpha-Reductase 1 Inhibitors for use in various applications. 5 alpha-Reductase 1 inhibitors are specialized compounds that target the enzyme 5α-reductase type 1, which is responsible for converting testosterone into dihydrotestosterone (DHT), a more potent androgen. This enzyme plays a crucial role in the metabolism of androgens, influencing various physiological processes such as hair growth, skin health, and the development of reproductive tissues. In scientific research, 5 alpha-Reductase 1 inhibitors are indispensable tools for studying the regulation of androgenic activity at the cellular level. Researchers utilize these inhibitors to explore the enzyme's role in endocrine pathways, understand its involvement in metabolic and developmental processes, and investigate its broader implications in conditions related to androgen excess or deficiency. These inhibitors are also valuable in the development of experimental models to study the effects of altered androgen levels on biological systems, providing insights into the complex dynamics of hormone regulation and action. The high purity and specificity of 5 alpha-Reductase 1 inhibitors provided by Santa Cruz Biotechnology ensure that experiments can be conducted with precision and reproducibility, yielding reliable data that advance scientific knowledge. By offering a comprehensive selection of these inhibitors, Santa Cruz Biotechnology supports the scientific community in uncovering novel insights into androgen metabolism and its regulation. View detailed information on our available 5 alpha-Reductase 1 Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Finasteride

98319-26-7sc-203954
50 mg
$103.00
3
(1)

Finasteride is a selective inhibitor of 5α-Reductase 1. It directly targets the enzyme responsible for converting testosterone to dihydrotestosterone (DHT), a potent androgen implicated in various physiological processes, including prostate growth. By inhibiting 5α-Reductase 1, Finasteride modulates androgen signaling pathways, leading to a reduction in DHT levels and therapeutic effects in conditions such as benign prostatic hyperplasia (BPH) and androgenetic alopecia.

Dutasteride

164656-23-9sc-207600
10 mg
$167.00
2
(1)

Dutasteride is a dual inhibitor of 5α-Reductase 1 and 5α-Reductase 2. Similar to Finasteride, Dutasteride hinders the conversion of testosterone to DHT by directly targeting 5α-Reductase enzymes. Its broader inhibition spectrum makes it effective in conditions like BPH, where both isoforms play a role. Dutasteride's impact on androgen levels and signaling pathways is central to its therapeutic actions, highlighting its relevance in managing androgen-related disorders.

Azelaic acid

123-99-9sc-257106
25 g
$41.00
(0)

Azelaic acid has demonstrated inhibitory effects on 5α-Reductase 1, suggesting a potential role in modulating androgen metabolism. The specific mechanisms of action involve interference with the enzymatic activity of 5α-Reductase 1, leading to a reduction in DHT levels. Azelaic acid's impact on androgen signaling pathways may contribute to its observed efficacy in conditions such as androgenetic alopecia and acne, where androgens play a significant role.

Caffeic Acid

331-39-5sc-200499
sc-200499A
1 g
5 g
$31.00
$61.00
1
(2)

Caffeic acid has shown inhibitory effects on 5α-Reductase 1, suggesting a potential role in modulating androgen metabolism. The specific mechanisms of action involve interference with the enzymatic activity of 5α-Reductase 1, leading to a reduction in DHT levels. Caffeic acid's impact on androgen signaling pathways may contribute to its observed efficacy in conditions such as androgenetic alopecia, where androgens play a significant role.

EGTA

67-42-5sc-3593
sc-3593A
sc-3593B
sc-3593C
sc-3593D
1 g
10 g
100 g
250 g
1 kg
$20.00
$62.00
$116.00
$246.00
$799.00
23
(1)

EGTA is a calcium chelator that has been implicated in modulating signaling pathways related to 5α-Reductase 1 activity. While the precise mechanisms are not fully elucidated, EGTA's ability to chelate calcium ions may impact calcium-dependent processes involved in androgen metabolism.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc has been associated with modulating 5α-Reductase 1 activity, potentially through its role in cellular processes related to androgen metabolism. While the exact mechanisms are not fully elucidated, zinc's impact on intracellular signaling pathways and enzymatic activity may contribute to its observed effects.