5 alpha-Reductase 1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $103.00 | 3 | |
Finasteride is a selective inhibitor of 5α-Reductase 1. It directly targets the enzyme responsible for converting testosterone to dihydrotestosterone (DHT), a potent androgen implicated in various physiological processes, including prostate growth. By inhibiting 5α-Reductase 1, Finasteride modulates androgen signaling pathways, leading to a reduction in DHT levels and therapeutic effects in conditions such as benign prostatic hyperplasia (BPH) and androgenetic alopecia. | ||||||
Dutasteride | 164656-23-9 | sc-207600 | 10 mg | $167.00 | 2 | |
Dutasteride is a dual inhibitor of 5α-Reductase 1 and 5α-Reductase 2. Similar to Finasteride, Dutasteride hinders the conversion of testosterone to DHT by directly targeting 5α-Reductase enzymes. Its broader inhibition spectrum makes it effective in conditions like BPH, where both isoforms play a role. Dutasteride's impact on androgen levels and signaling pathways is central to its therapeutic actions, highlighting its relevance in managing androgen-related disorders. | ||||||
Azelaic acid | 123-99-9 | sc-257106 | 25 g | $41.00 | ||
Azelaic acid has demonstrated inhibitory effects on 5α-Reductase 1, suggesting a potential role in modulating androgen metabolism. The specific mechanisms of action involve interference with the enzymatic activity of 5α-Reductase 1, leading to a reduction in DHT levels. Azelaic acid's impact on androgen signaling pathways may contribute to its observed efficacy in conditions such as androgenetic alopecia and acne, where androgens play a significant role. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $31.00 $61.00 | 1 | |
Caffeic acid has shown inhibitory effects on 5α-Reductase 1, suggesting a potential role in modulating androgen metabolism. The specific mechanisms of action involve interference with the enzymatic activity of 5α-Reductase 1, leading to a reduction in DHT levels. Caffeic acid's impact on androgen signaling pathways may contribute to its observed efficacy in conditions such as androgenetic alopecia, where androgens play a significant role. | ||||||
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $20.00 $62.00 $116.00 $246.00 $799.00 | 23 | |
EGTA is a calcium chelator that has been implicated in modulating signaling pathways related to 5α-Reductase 1 activity. While the precise mechanisms are not fully elucidated, EGTA's ability to chelate calcium ions may impact calcium-dependent processes involved in androgen metabolism. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc has been associated with modulating 5α-Reductase 1 activity, potentially through its role in cellular processes related to androgen metabolism. While the exact mechanisms are not fully elucidated, zinc's impact on intracellular signaling pathways and enzymatic activity may contribute to its observed effects. | ||||||