Biperiden hydrochloride A muscarinic receptor antagonist

Biperiden hydrochloride (CAS 1235-82-1)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 62ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: Akineton; Akinophyl
Application: A muscarinic receptor antagonist
CAS Number: 1235-82-1
Purity: ≥97%
Molecular Weight: 347.92
Molecular Formula: C21H29NO•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Biperiden hydrochloride is a muscarinic receptor (mAChR M) antagonist that displays some selectivity for the mAChR M1 subtype (Ki values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for mAChR M1, mAChR M4, mAChR M3, mAChR M2 and mAChR M5 receptors, respectively).


Bolden et al (1992) Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in chinese hamster ovary cells. J.Pharmacol.Exp.Ther. 260 576. Sudo et al (1999) Muscarinic receptor occupancy by biperiden in living human brain. Life Sci. 64 PL99. Brocks (1999) Anticholienrgic drugs used in Parkinson's disease: an overlooked class of drugs from a pharmacokinetic perspective. J.Pharm.Pharmaceut.Sci. 2 39.

Physical State :
Solubility :
Soluble in water (5 mM), DMSO (10 mM), and methanol.
Storage :
Desiccate at 4° C
Melting Point :
>240° C (dec.)
Refractive Index :
n20D ~1.58 (Predicted)
Ki Data :
mAChR M1 : Ki= 0.48 nM; mAChR M4 : Ki= 2.4 nM; mAChR M3 : Ki= 3.9 nM; mAChR M2 : Ki= 6.3 nM; mAChR M5 : Ki= 6.3 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 1233
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 66ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 3ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.