Date published: 2025-10-15

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Apaf-1 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Apaf-1 antibodies for research focused on understanding apoptosis and cellular signaling. Apaf-1 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Apaf-1, or apoptotic protease activating factor 1, is a crucial component of the apoptosome, playing a significant role in the intrinsic pathway of apoptosis. By facilitating the activation of caspases, Apaf-1 is essential for programmed cell death, which is vital for maintaining cellular homeostasis and development. Dysregulation of Apaf-1 has been implicated in various diseases, including cancer, making it an important target for therapeutic research. Researchers can use Apaf-1 antibodies to explore the mechanisms of cell death and their connection to disease progression. Apaf-1 antibodies enable detailed examination of Apaf-1's interactions with other proteins in the apoptotic pathway. Scientists can investigate how Apaf-1 expression levels change under different conditions and in various cell types.

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Apaf-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Apaf-1 Antibody (5E11)

sc-65891mouse IgG1 κC-Terminal (h)WB, IP, IF, IHC(P)m, r, h
22
(4)

Apaf-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Apaf-1 CRISPR/Cas9 KO Plasmid (h)

sc-401291hGene KnockoutGFP
1
(0)

Apaf-1 HDR Plasmid (h)

sc-401291-HDRhHomology Directed RepairPuromycin
1
(0)

Apaf-1 Double Nickase Plasmid (h)

sc-401291-NIChGene KnockoutPuromycin
1
(0)

Apaf-1 Double Nickase Plasmid (h2)

sc-401291-NIC-2hGene KnockoutPuromycin
1
(0)

Apaf-1 CRISPR/Cas9 KO Plasmid (m)

sc-419142mGene KnockoutGFP0
(0)

Apaf-1 HDR Plasmid (m)

sc-419142-HDRmHomology Directed RepairPuromycin0
(0)

Apaf-1 Double Nickase Plasmid (m)

sc-419142-NICmGene KnockoutPuromycin0
(0)

Apaf-1 Double Nickase Plasmid (m2)

sc-419142-NIC-2mGene KnockoutPuromycin0
(0)

Apaf-1 CRISPR Activation Products

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Apaf-1 CRISPR Activation Plasmid (h)

sc-401291-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Apaf-1 CRISPR Activation Plasmid (h2)

sc-401291-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Apaf-1 Lentiviral Activation Particles (h)

sc-401291-LAChGene ActivationPuro, Blast, Hygro
1
(0)

Apaf-1 Lentiviral Activation Particles (h2)

sc-401291-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

Apaf-1 CRISPR Activation Plasmid (m)

sc-419142-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Apaf-1 CRISPR Activation Plasmid (m2)

sc-419142-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Apaf-1 Lentiviral Activation Particles (m)

sc-419142-LACmGene ActivationPuro, Blast, Hygro0
(0)

Apaf-1 Lentiviral Activation Particles (m2)

sc-419142-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Apaf-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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Apaf-1 siRNA (h)

sc-29201hGene SilencingN/A
5
(0)

Apaf-1 shRNA Plasmid (h)

sc-29201-SHhGene SilencingPuromycin
5
(0)

Apaf-1 shRNA (h) Lentiviral Particles

sc-29201-VhGene SilencingPuromycin
5
(0)

Apaf-1 siRNA (m)

sc-37147mGene SilencingN/A0
(0)

Apaf-1 shRNA Plasmid (m)

sc-37147-SHmGene SilencingPuromycin0
(0)

Apaf-1 shRNA (m) Lentiviral Particles

sc-37147-VmGene SilencingPuromycin0
(0)