Date published: 2025-9-9

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X11α Anticorpo (C-2): sc-137023

5.0(2)
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Fichas de dados
  • X11 alpha Anticorpo C-2é um anticorpo monoclonal produzido em camundongo IgG1 (kappa light chain) fornecido em 200 µg/ml
  • raised against amino acids 1-265 mapping near the N-terminus of X11α of human origin
  • recomendado para a detecção de X11α de mouse, rat e human origem em
  • m-IgG Fc BP-HRP e 1 BP-HRP">m-IgG1 BP-HRP são os reagentes de deteção secundários preferidos para X11α Antibody (C-2) for WB applications. Estes reagentes são agora oferecidos em conjuntos com X11α Antibody (C-2)(ver informações de encomenda abaixo).

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    The β-Amyloid precursor protein (β-APP) is a major constituent of the amyloid deposits in patients with Alzheimer's disease. The β-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the β-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular β-APP and slowing β-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of β-APP. Multiple splice varitents of X11 have been identified, including X11α (also designated Mint 1), X11β (Mint 2) and X11γ (Mint 3).

    Para uso em exclusivo em pesquisa. Não se destina a uso em diagnostico e tratamento.

    Informacoes sobre ordens

    Nome do ProdutoNumero de CatalogoUNIDPrecoQdeFAVORITOS

    X11α Anticorpo (C-2)

    sc-137023
    200 µg/ml
    $316.00

    Pacote do X11α (C-2): m-IgG Fc BP-HRP

    sc-539917
    200 µg Ab; 10 µg BP
    $354.00

    Pacote do X11α (C-2): m-IgG1 BP-HRP

    sc-541785
    200 µg Ab; 20 µg BP
    $354.00

    What blocking solution should I use with X11α (C-2): sc-137023 monoclonal antibody for Western blot?

    Asked by: Germaine
    Thank you for your question. We recommend blocking with Blotto (either TBS Blotto A: sc-2333 or TBS Blotto B: sc-2335). Our Western blot protocol can be found here: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Nice Western Blot data of X11 expressionNice Western Blot data of X11 expression in rat brain tissue extract. -SCBT QC
    Date published: 2015-03-28
    Rated 5 out of 5 by from Nice Western Blot data of X11 expressionNice Western Blot data of X11 expression in rat cerebellum and mouse brain tissue extracts. -SCBT QC
    Date published: 2013-04-29
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    X11α Anticorpo (C-2) is rated 5.0 out of 5 by 2.
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