RCL Antibody (A-7): sc-365683

RCL Antibody (A-7) is a mouse monoclonal IgG3 kappa light chain antibody that detects RCL protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-RCL antibody (A-7) is available as non-conjugated format. RCL protein, consisting of 174 amino acids, is a member of the deoxyribonucleoside 5′-monophosphate N-glycosidase family and plays a crucial role in cellular proliferation and c-Myc-mediated transformation, making RCL significant in cancer biology and therapeutic research. RCL is predominantly expressed in heart, kidney, liver, skeletal muscle, and spleen, with lower expression levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus, and shows notable overexpression in a significant proportion of breast cancers. RCL protein is localized in both nucleus and cytoplasm, with expression being induced by transcription factor ER81. RCL gene is highly conserved across species, including chimpanzee, dog, mouse, rat, and zebrafish, and is located on human chromosome 6p21.1, a region harboring approximately 1,200 genes and implicated in various genetic disorders. Understanding RCL function and expression patterns is essential for elucidating RCL role in cellular processes and potential as a biomarker or therapeutic target in cancer and other diseases.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-RCL Antibody (A-7) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-RCL Antibody (A-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

RCL Antibody (A-7) Specifications

Alternate Product Name: RCL

Product Clone Name: A-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 1-174

Epitope Target: RCL

Epitope Species: human

Product Reactivity/Detection: RCL

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for RCL Antibody (A-7): N/A

The preferred RCL antibody is RCL Antibody (C-8): sc-365682.