Plk Antibody (AZ27): sc-53419
- Plk Antibody (AZ27) is a mouse monoclonal IgG2b provided at 200 µg/ml
- raised against Plk of Xenopus origin
- recommended for detection of Plk of mouse, rat, human and Xenopus origin by WB and IP
- See Plk (F-8): sc-17783 for Plk antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Plk Antibody (AZ27). This work is in progress.
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SEE ALSO...
Plk Antibody (AZ27) is a mouse monoclonal IgG2b light chain antibody that detects Plk in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Plk, or polo-like kinase, plays a crucial role in cell cycle regulation, particularly during the transition from the G2 phase to mitosis, where Plk is essential for the proper functioning of the mitotic spindle. Plk activity is tightly regulated, with Plk levels peaking at the onset of mitosis, which is vital for ensuring accurate chromosome segregation and preventing aneuploidy. Plk presence is particularly notable in mitotically active tissues, including the colon and placenta, as well as in various tumors, suggesting Plk potential as a biomarker for cell proliferation and cancer progression. Anti-Plk antibody (AZ27) provides a reliable tool for researchers investigating the dynamics of cell division and the implications of Plk in oncogenesis, enabling deeper insights into the mechanisms of cell cycle regulation and associated pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Plk Antibody (AZ27) | sc-53419 | 200 µg/ml | $322.00 |