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IKKγ Antibody (46B844) is a mouse monoclonal IgG1 antibody engineered to recognize the full-length native IKKγ protein, also known as NEMO (NF-κB Essential Modulator), of human origin. Anti-IKKγ antibody (46B844) is ideal for detecting IKKγ in various applications including western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA), ensuring reliable and consistent performance in your research. IKKγ is a vital component of the IKK complex located in the cytoplasm, where IKKγ plays a crucial role in the activation of the NF-κB signaling pathway. By facilitating the phosphorylation and degradation of IκB inhibitors, IKKγ enables the translocation of NF-κB transcription factors to the nucleus, thereby regulating genes involved in immune responses, inflammation, and cell survival. Understanding the cellular localization and function of IKKγ is essential for studying how cells respond to proinflammatory cytokines and stress signals, as well as IKKγ′s involvement in diseases such as cancer and autoimmune disorders. IKKγ monoclonal antibody (46B844) is recommended for scientists investigating the molecular mechanisms of NF-κB activation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IKKγ Antibody (46B844) | sc-52930 | 100 µg/ml | $339.00 |