Flt-3/Flk-2 Antibody (BV10): sc-21788
- Flt-3/Flk-2 Antibody (BV10) is a mouse monoclonal mouse IgG1 κ κ provided at 200 µg/ml
- raised against pro B-cell line BV-173
- recommended for detection of Flt-3/Flk-2 p160 and p130 of human origin by WB, IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See Flt-3/Flk-2 (SF1.340): sc-19635 for Flt-3/Flk-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Flt-3/Flk-2 Antibody (BV10). This work is in progress.
QUICK LINKS
Flt-3/Flk-2 Antibody (BV10) is a mouse monoclonal IgG1 antibody that detects Flt-3/Flk-2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Flt-3/Flk-2, also known as stem cell tyrosine kinase (STK-1), plays a crucial role in hematopoiesis as a member of the type III receptor tyrosine kinase family, which includes other important receptors like Kit and PDGF. Flt-3/Flk-2 is primarily expressed in CD34+ hematopoietic stem and progenitor cells, highlighting its significance in the regulation of stem cell proliferation and differentiation. The interaction of Flt-3/Flk-2 with various ligands, such as Flt-3 ligand, is essential for the survival and expansion of these progenitor cells, making Flt-3/Flk-2 a key player in the development of the hematopoietic system. Additionally, Flt-3/Flk-2 has been implicated in the pathogenesis of certain leukemias, underscoring its importance as a potential therapeutic target. Anti-Flt-3/Flk-2 antibody (BV10) recognizes two polypeptides in CD34+ cells, providing valuable insights into the functional dynamics of hematopoietic stem cells and their progenitors.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Flt-3/Flk-2 Antibody (BV10) | sc-21788 | 200 µg/ml | $322.00 | |||
Flt-3/Flk-2 Antibody (BV10) FITC | sc-21788 FITC | 200 µg/ml | $336.00 | |||
Flt-3/Flk-2 Antibody (BV10) PE | sc-21788 PE | 200 µg/ml | $349.00 |