Date published: 2026-8-12

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OPN Antibodies

Santa Cruz Biotechnology features a diverse variety of OPN Antibodies for research focused on understanding osteopontin (OPN) in various biological processes. OPN Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Osteopontin is a glycoprotein that plays a critical role in cell signaling, immune response, and tissue remodeling. OPN is involved in various physiological and pathological processes, including bone mineralization, inflammation, and cancer progression. Understanding osteopontin function is essential for advancing research in osteoporosis, cardiovascular diseases, and certain cancers. Monoclonal OPN antibodies enable precise detection and characterization of osteopontin expression patterns across different tissues and experimental conditions. Researchers can utilize specific OPN monoclonal antibodies to investigate cellular pathways and molecular mechanisms. Advanced research techniques incorporating OPN monoclonal antibodies help unlock new insights about disease mechanisms and potential therapeutic targets. Santa Cruz Biotechnology monoclonal OPN antibodies contribute to advancing scientific understanding of disease processes and potential treatments.

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OPN Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

osteopontin/OPN/SPP1 Antibody (AKm2A1)

sc-21742mouse IgG1 κ(m)WB, IP, IF, IHC(P)m, r, h
365
(28)

osteopontin/OPN/SPP1 Antibody (LFMb-14)

sc-73631mouse IgG2b κFL (h)WB, IP, IF, IHC(P), FCMm, r, h
61
(7)

OPN siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

osteopontin/OPN/SPP1 siRNA (h)

sc-36129hGene SilencingN/A
9
(0)

osteopontin/OPN/SPP1 shRNA Plasmid (h)

sc-36129-SHhGene SilencingPuromycin
9
(0)

osteopontin/OPN/SPP1 shRNA (h) Lentiviral Particles

sc-36129-VhGene SilencingPuromycin
9
(0)

osteopontin/OPN/SPP1 siRNA (m)

sc-36130mGene SilencingN/A
8
(0)

osteopontin/OPN/SPP1 shRNA Plasmid (m)

sc-36130-SHmGene SilencingPuromycin
8
(0)

osteopontin/OPN/SPP1 shRNA (m) Lentiviral Particles

sc-36130-VmGene SilencingPuromycin
8
(0)

osteopontin/OPN/SPP1 siRNA (r)

sc-270052rGene SilencingN/A
1
(0)

osteopontin/OPN/SPP1 shRNA Plasmid (r)

sc-270052-SHrGene SilencingPuromycin
1
(0)

osteopontin/OPN/SPP1 shRNA (r) Lentiviral Particles

sc-270052-VrGene SilencingPuromycin
1
(0)

osteopontin/OPN/SPP1 siRNA (bovine)

sc-156029bovineGene SilencingN/A0
(0)

OPN CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

osteopontin/OPN/SPP1 CRISPR/Cas9 KO Plasmid (h2)

sc-400219-KO-2Gene Knockouth0
(0)

osteopontin/OPN/SPP1 HDR Plasmid (h2)

sc-400219-HDR-2Homology Directed Repairh0
(0)

osteopontin/OPN/SPP1 CRISPR/Cas9 KO Plasmid (m)

sc-423134Gene Knockoutm0
(0)

osteopontin/OPN/SPP1 HDR Plasmid (m)

sc-423134-HDRHomology Directed Repairm0
(0)

OPN CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

osteopontin/OPN/SPP1 Double Nickase Plasmid (h)

sc-400219-NICGene Knockouth0
(0)

osteopontin/OPN/SPP1 Double Nickase Plasmid (h2)

sc-400219-NIC-2Gene Knockouth0
(0)

osteopontin/OPN/SPP1 Double Nickase Plasmid (m)

sc-423134-NICGene Knockoutm0
(0)

osteopontin/OPN/SPP1 Double Nickase Plasmid (m2)

sc-423134-NIC-2Gene Knockoutm0
(0)

OPN CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

osteopontin/OPN/SPP1 CRISPR Activation Plasmid (h)

sc-400219-ACTGene Activationh0
(0)

osteopontin/OPN/SPP1 CRISPR Activation Plasmid (h2)

sc-400219-ACT-2Gene Activationh0
(0)

osteopontin/OPN/SPP1 CRISPR Activation Plasmid (m)

sc-423134-ACTGene Activationm0
(0)

osteopontin/OPN/SPP1 CRISPR Activation Plasmid (m2)

sc-423134-ACT-2Gene Activationm0
(0)

osteopontin/OPN/SPP1 Lentiviral Activation Particles (m)

sc-423134-LACGene Activationm0
(0)