DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.
The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.
VEJA TAMBÉM
Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
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α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
A α-Amanitina inibe a RNA polimerase II, dificultando a transcrição e impedindo a síntese do mRNA do DGCR6L. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
A puromicina induz a terminação prematura da síntese proteica, afectando a tradução e diminuindo os níveis de DGCR6L. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
A actinomicina C1 liga-se ao ADN e inibe a transcrição, levando a uma diminuição da expressão de DGCR6L. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $99.00 | 5 | |
A cordicepina interfere com a síntese de ARNm, afectando a transcrição e contribuindo para a regulação negativa do DGCR6L. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $311.00 | ||
O flavopiridol é um inibidor da quinase dependente da ciclina, que impede a fosforilação da RNA polimerase II e inibe a transcrição do DGCR6L. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $142.00 $558.00 | 4 | |
A elipticina intercala-se no ADN, inibindo a transcrição e conduzindo a uma diminuição da expressão de DGCR6L. | ||||||
Streptonigrin | 3930-19-6 | sc-500892 sc-500892A | 1 mg 5 mg | $102.00 $357.00 | 1 | |
A estreptolidigina inibe a RNA polimerase bacteriana, afectando indiretamente a expressão de DGCR6L ao interferir com a transcrição. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
O ácido micofenólico inibe a inosina monofosfato desidrogenase, afectando indiretamente a expressão de DGCR6L através da perturbação da síntese de purinas. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $360.00 $475.00 | 20 | |
A blasticidina S induz a terminação prematura durante a tradução, inibindo a síntese proteica e reduzindo os níveis de DGCR6L. |