ZNF785 Antibody (C-9): sc-398676

ZNF785 Antibody (C-9) is a mouse monoclonal IgM antibody that detects ZNF785 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ZNF785 antibody (C-9) is available as a non-conjugated monoclonal isotype antibody. ZNF785, a member of the Krüppel C2H2-type zinc-finger protein family, plays a crucial role in transcriptional regulation due to its ability to bind DNA through seven C2H2-type zinc fingers and one KRAB domain. This domain interacts with KAP1 protein, which recruits histone-modifying enzymes that can alter chromatin structure and influence gene expression. Two isoforms of ZNF785, resulting from alternative splicing, add another layer of complexity to regulatory functions, potentially allowing for diverse roles in cellular processes. Understanding ZNF785 function is vital, as ZNF785 may be implicated in various biological processes and diseases, making ZNF785 a valuable target for research in gene regulation and therapeutic interventions.

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ZNF785 Antibody (C-9) References:

1. Physical mapping and evolution of the centromeric class I gene-containing region of the rat MHC.  |  Walter, L. and Günther, E. 2000. Immunogenetics. 51: 829-37. PMID: 10970097
2. Identification of multiple differentially expressed messenger RNAs in normal and pathological trophoblast.  |  Durand, S., et al. 2003. Placenta. 24: 209-18. PMID: 12566248
3. [Progress in the study of KRAB zinc finger protein].  |  Tian, CY., et al. 2006. Yi Chuan. 28: 1451-6. PMID: 17098717
4. Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors.  |  Liu, J. and Stormo, GD. 2008. Bioinformatics. 24: 1850-7. PMID: 18586699
5. Multiple genes encoding zinc finger domains are expressed in human T cells.  |  Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
6. Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins.  |  Berg, JM. 1988. Proc Natl Acad Sci U S A. 85: 99-102. PMID: 3124104
7. Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes.  |  Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
8. Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.  |  Abrink, M., et al. 1995. DNA Cell Biol. 14: 125-36. PMID: 7865130
9. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs.  |  Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF785 Antibody (C-9) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF785 Antibody (C-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF785 Antibody (C-9) Specifications

Alternate Product Name: ZNF785

Product Clone Name: C-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 13-34

Epitope Target: ZNF785

Epitope Species: human

Product Reactivity/Detection: ZNF785

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF785 Antibody (C-9): P: Blocking Peptide