ZNF688 Antibody (B-3): sc-390334
- ZNF688 Antibody (B-3) is a mouse monoclonal IgG1 κ ZNF688 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 248-261 near the C-terminus of ZNF688 of human origin
- ZNF688 Antibody (B-3) is recommended for detection of ZNF688 isoforms 1 and 3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNF688 Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for ZNF688 Antibody (B-3) for WB applications. This reagent is now offered in a bundle with ZNF688 Antibody (B-3) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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ZNF688 Antibody (B-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF688 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF688 (B-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Zinc finger protein 688 (ZNF688) is a 276 amino acid protein that belongs to the Krüppel C2H2-type zinc-finger protein family, which is characterized by its ability to bind DNA and regulate transcription. ZNF688 is primarily localized in the nucleus, where ZNF688 plays a crucial role in gene expression by interacting with specific DNA sequences. ZNF688 contains two C2H2-type zinc fingers and a KRAB domain, which is believed to facilitate ZNF688′s interaction with KAP1, a corepressor that recruits histone-modifying enzymes to regulate chromatin structure and gene accessibility. This function is vital for maintaining proper cellular processes, including differentiation and response to environmental signals, making ZNF688 an important player in the regulation of gene expression and cellular homeostasis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF688 Antibody (B-3) References:
- Physical mapping and evolution of the centromeric class I gene-containing region of the rat MHC. | Walter, L. and Günther, E. 2000. Immunogenetics. 51: 829-37. PMID: 10970097
- Identification of multiple differentially expressed messenger RNAs in normal and pathological trophoblast. | Durand, S., et al. 2003. Placenta. 24: 209-18. PMID: 12566248
- [Progress in the study of KRAB zinc finger protein]. | Tian, CY., et al. 2006. Yi Chuan. 28: 1451-6. PMID: 17098717
- Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors. | Liu, J. and Stormo, GD. 2008. Bioinformatics. 24: 1850-7. PMID: 18586699
- Multiple genes encoding zinc finger domains are expressed in human T cells. | Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
- Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins. | Berg, JM. 1988. Proc Natl Acad Sci U S A. 85: 99-102. PMID: 3124104
- Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes. | Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
- Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. | Abrink, M., et al. 1995. DNA Cell Biol. 14: 125-36. PMID: 7865130
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. | Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF688 Antibody (B-3) | sc-390334 | 200 µg/ml | $322.00 | |||
ZNF688 Antibody (B-3): m-IgGκ BP-HRP Bundle | sc-523495 | 200 µg Ab, 40 µg BP | $361.00 | |||
ZNF688 Antibody (B-3) AC | sc-390334 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZNF688 Antibody (B-3) HRP | sc-390334 HRP | 200 µg/ml | $322.00 | |||
ZNF688 Antibody (B-3) FITC | sc-390334 FITC | 200 µg/ml | $336.00 | |||
ZNF688 Antibody (B-3) PE | sc-390334 PE | 200 µg/ml | $349.00 | |||
ZNF688 Antibody (B-3) Alexa Fluor® 488 | sc-390334 AF488 | 200 µg/ml | $364.00 | |||
ZNF688 Antibody (B-3) Alexa Fluor® 546 | sc-390334 AF546 | 200 µg/ml | $364.00 | |||
ZNF688 Antibody (B-3) Alexa Fluor® 594 | sc-390334 AF594 | 200 µg/ml | $364.00 | |||
ZNF688 Antibody (B-3) Alexa Fluor® 647 | sc-390334 AF647 | 200 µg/ml | $364.00 | |||
ZNF688 Antibody (B-3) Alexa Fluor® 680 | sc-390334 AF680 | 200 µg/ml | $364.00 | |||
ZNF688 Antibody (B-3) Alexa Fluor® 790 | sc-390334 AF790 | 200 µg/ml | $364.00 | |||
ZNF688 (B-3) Neutralizing Peptide | sc-390334 P | 100 µg/0.5 ml | $69.00 |