ZNF659 Antibody (C-11): sc-514040

ZNF659 Antibody (C-11) is a mouse monoclonal IgM antibody that detects ZNF659 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ZNF659 antibody (C-11) is available as a non-conjugated format. ZNF659, also known as Zinc finger protein 385D, is a crucial nuclear protein composed of 395 amino acids and features three C2H2-type zinc finger domains, which are essential for RNA binding and gene regulation. These zinc fingers allow ZNF659 to interact with specific RNA molecules, influencing various cellular processes, including transcriptional regulation and mRNA processing. Such interaction is vital for maintaining proper gene expression and cellular function, as dysregulation of ZNF659 has been implicated in several diseases, including cancer. The gene encoding ZNF659 is located on human chromosome 3, a region rich in genes associated with critical biological functions and disease pathways. ZNF659 Antibody (C-11) enables researchers to gain valuable insights into cellular mechanisms and potential implications in health and disease.

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ZNF659 Antibody (C-11) References:

1. Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution.  |  Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
2. [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification].  |  Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
3. The SCAN domain family of zinc finger transcription factors.  |  Edelstein, LC. and Collins, T. 2005. Gene. 359: 1-17. PMID: 16139965
4. A search for variants associated with young-onset type 2 diabetes in American Indians in a 100K genotyping array.  |  Hanson, RL., et al. 2007. Diabetes. 56: 3045-52. PMID: 17846125
5. Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors.  |  Liu, J. and Stormo, GD. 2008. Bioinformatics. 24: 1850-7. PMID: 18586699
6. Evolutionary plasticity and cancer breakpoints in human chromosome 3.  |  Ruiz-Herrera, A. and Robinson, TJ. 2008. Bioessays. 30: 1126-37. PMID: 18937354
7. Multiple genes encoding zinc finger domains are expressed in human T cells.  |  Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
8. Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes.  |  Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
9. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs.  |  Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF659 Antibody (C-11) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF659 Antibody (C-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF659 Antibody (C-11) Specifications

Alternate Product Name: ZNF659

Product Clone Name: C-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 178-202

Epitope Target: ZNF659

Epitope Species: human

Product Reactivity/Detection: ZNF659

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF659 Antibody (C-11): P: Blocking Peptide