ZNF345 Antibody (38-H): sc-101081

ZNF345 Antibody (38-H) is a mouse monoclonal IgG2b kappa light chain antibody that detects ZNF345 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-ZNF345 antibody (38-H) is available as the non-conjugated format. ZNF345, also known as HZF10, is a 488 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family, which binds DNA and regulates transcription. ZNF345 is primarily localized in the nucleus, where ZNF345 plays a crucial role in gene expression by functioning as a transcriptional regulator. The presence of fifteen C2H2-type zinc fingers within ZNF345′s structure allows specific DNA sequence interactions, thereby influencing target gene transcription. This regulatory function is vital for various cellular processes, including development, differentiation, and response to environmental signals. ZNF345 also interacts with other proteins, such as KAP1, which participates in chromatin remodeling and transcriptional repression, highlighting ZNF345′s importance in the intricate network of gene regulation.

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ZNF345 Antibody (38-H) References:

1. The zinc finger-associated SCAN box is a conserved oligomerization domain.  |  Williams, AJ., et al. 1999. Mol Cell Biol. 19: 8526-35. PMID: 10567577
2. The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL.  |  Rousseau-Merck, MF., et al. 2002. Cytogenet Genome Res. 98: 147-53. PMID: 12697996
3. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.  |  Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
4. Multiple genes encoding zinc finger domains are expressed in human T cells.  |  Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
5. Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.  |  Abrink, M., et al. 1995. DNA Cell Biol. 14: 125-36. PMID: 7865130
6. Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.  |  Rousseau-Merck, MF., et al. 1993. Hum Genet. 92: 583-7. PMID: 8262519

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF345 Antibody (38-H) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF345 Antibody (38-H) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF345 Antibody (38-H) Specifications

Alternate Product Name: ZNF345

Product Clone Name: 38-H

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1-112

Epitope Target: ZNF345

Epitope Species: human

Product Reactivity/Detection: ZNF345

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 50 µg IgG_2b kappa light chain in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF345 Antibody (38-H): N/A