ZNF296 Antibody (C-12): sc-514868
- ZNF296 Antibody (C-12) is a mouse monoclonal IgG1 κ ZNF296 antibody provided at 200 µg/ml
- raised against amino acids 1-202 mapping raised against aa 1-202 of ZNF296 of human origin of ZNF296 of human origin
- ZNF296 Antibody (C-12) is recommended for detection of ZNF296 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNF296 Antibody (C-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZNF296 Antibody (C-12) for WB applications. These reagents are now offered in bundles with ZNF296 Antibody (C-12) (see ordering information below).
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ZNF296 Antibody (C-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF296 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF296 Antibody (C-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF296, also known as zinc finger protein 342, is a crucial nuclear protein composed of 475 amino acids and features six C2H2-type zinc fingers, which are essential for DNA-binding and transcriptional regulation. ZNF296 is primarily located in the nucleus, where ZNF296 plays a significant role in modulating gene expression, thereby influencing various cellular processes such as differentiation, proliferation, and response to environmental stimuli. ZNF296′s ability to interact with specific DNA sequences allows ZNF296 to act as a transcription factor, which is vital for maintaining cellular homeostasis and regulating developmental pathways. Understanding ZNF296′s function and regulatory mechanisms is important for elucidating potential implications in diseases, including cancer, where dysregulation of transcription factors can lead to aberrant gene expression and tumorigenesis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF296 Antibody (C-12) References:
- [Progress in the study of KRAB zinc finger protein]. | Tian, CY., et al. 2006. Yi Chuan. 28: 1451-6. PMID: 17098717
- Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors. | Liu, J. and Stormo, GD. 2008. Bioinformatics. 24: 1850-7. PMID: 18586699
- Multiple genes encoding zinc finger domains are expressed in human T cells. | Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
- Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins. | Berg, JM. 1988. Proc Natl Acad Sci U S A. 85: 99-102. PMID: 3124104
- Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes. | Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
- Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. | Abrink, M., et al. 1995. DNA Cell Biol. 14: 125-36. PMID: 7865130
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. | Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF296 Antibody (C-12) | sc-514868 | 200 µg/ml | $322.00 | |||
ZNF296 Antibody (C-12): m-IgG Fc BP-HRP Bundle | sc-527953 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZNF296 Antibody (C-12): m-IgG1 BP-HRP Bundle | sc-533326 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZNF296 Antibody (C-12) AC | sc-514868 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZNF296 Antibody (C-12) HRP | sc-514868 HRP | 200 µg/ml | $322.00 | |||
ZNF296 Antibody (C-12) FITC | sc-514868 FITC | 200 µg/ml | $336.00 | |||
ZNF296 Antibody (C-12) PE | sc-514868 PE | 200 µg/ml | $349.00 | |||
ZNF296 Antibody (C-12) Alexa Fluor® 488 | sc-514868 AF488 | 200 µg/ml | $364.00 | |||
ZNF296 Antibody (C-12) Alexa Fluor® 546 | sc-514868 AF546 | 200 µg/ml | $364.00 | |||
ZNF296 Antibody (C-12) Alexa Fluor® 594 | sc-514868 AF594 | 200 µg/ml | $364.00 | |||
ZNF296 Antibody (C-12) Alexa Fluor® 647 | sc-514868 AF647 | 200 µg/ml | $364.00 | |||
ZNF296 Antibody (C-12) Alexa Fluor® 680 | sc-514868 AF680 | 200 µg/ml | $364.00 | |||
ZNF296 Antibody (C-12) Alexa Fluor® 790 | sc-514868 AF790 | 200 µg/ml | $364.00 |