ZNF271 Antibody (A-3): sc-377498
- ZNF271 Antibody (A-3) is a mouse monoclonal IgG1 κ ZNF271 antibody provided at 200 µg/ml
- raised against amino acids 1-100 mapping at the N-terminus of ZNF271 of mouse origin
- ZNF271 Antibody (A-3) is recommended for detection of ZNF271 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNF271 Antibody (A-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-377498 X, 200 µg/0.1 ml)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ZNF271 Antibody (A-3). This work is in progress.
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ZNF271 Antibody (A-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF271 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF271 (A-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF271, also known as zinc finger protein 271, zinc finger protein 7, and Epstein-Barr virus-induced zinc finger protein, is a 655 amino acid nuclear protein characterized by 19 C2H2-type zinc fingers. ZNF271 is primarily located in the nucleus, where ZNF271 plays a crucial role in regulating gene expression through DNA-binding capabilities. The presence of zinc-finger domains allows ZNF271 to interact with specific DNA sequences, thereby influencing transcriptional activation or repression, which is vital for cellular processes such as differentiation and response to viral infections. ZNF271 is implicated in the transformation of cells by the Epstein-Barr virus, highlighting ZNF271′s importance in both normal cellular function and disease states, particularly in hematopoietic malignancies, as the gene encoding ZNF271 is often found in chromosomal regions associated with these conditions. ZNF271 has two isoforms produced through alternative splicing, further diversifying ZNF271′s functional roles in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF271 Antibody (A-3) References:
- Sustained expression of the novel EBV-induced zinc finger gene, ZNFEB, is critical for the transition of B lymphocyte activation to oncogenic growth transformation. | Tune, CE., et al. 2002. J Immunol. 168: 680-8. PMID: 11777961
- Mapping of a gene for alopecia with mental retardation syndrome (APMR3) on chromosome 18q11.2-q12.2. | Wali, A., et al. 2007. Ann Hum Genet. 71: 570-7. PMID: 17451405
- Regulation and dysregulation of Epstein-Barr virus latency: implications for the development of autoimmune diseases. | Niller, HH., et al. 2008. Autoimmunity. 41: 298-328. PMID: 18432410
- Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors. | Liu, J. and Stormo, GD. 2008. Bioinformatics. 24: 1850-7. PMID: 18586699
- Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes. | Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
- Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. | Abrink, M., et al. 1995. DNA Cell Biol. 14: 125-36. PMID: 7865130
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. | Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF271 Antibody (A-3) | sc-377498 | 200 µg/ml | $322.00 | |||
ZNF271 Antibody (A-3) X | sc-377498 X | 200 µg/0.1 ml | $322.00 | |||
ZNF271 Antibody (A-3) AC | sc-377498 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZNF271 Antibody (A-3) HRP | sc-377498 HRP | 200 µg/ml | $322.00 | |||
ZNF271 Antibody (A-3) FITC | sc-377498 FITC | 200 µg/ml | $336.00 | |||
ZNF271 Antibody (A-3) PE | sc-377498 PE | 200 µg/ml | $349.00 | |||
ZNF271 Antibody (A-3) Alexa Fluor® 488 | sc-377498 AF488 | 200 µg/ml | $364.00 | |||
ZNF271 Antibody (A-3) Alexa Fluor® 546 | sc-377498 AF546 | 200 µg/ml | $364.00 | |||
ZNF271 Antibody (A-3) Alexa Fluor® 594 | sc-377498 AF594 | 200 µg/ml | $364.00 | |||
ZNF271 Antibody (A-3) Alexa Fluor® 647 | sc-377498 AF647 | 200 µg/ml | $364.00 | |||
ZNF271 Antibody (A-3) Alexa Fluor® 680 | sc-377498 AF680 | 200 µg/ml | $364.00 | |||
ZNF271 Antibody (A-3) Alexa Fluor® 790 | sc-377498 AF790 | 200 µg/ml | $364.00 |