ZNF263 Antibody (8-YD33): sc-135612

ZNF263 Antibody (8-YD33) is a mouse monoclonal IgG2a kappa light chain antibody that detects the ZNF263 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-ZNF263 antibody (8-YD33) is available as a non-conjugated format. ZNF263, also known as FPM315 or ZKSCAN12, is a crucial transcriptional repressor located in the nucleus, where ZNF263 plays a significant role in regulating gene expression. ZNF263 is characterized by nine C2H2-type zinc fingers, a KRAB domain, and a SCAN box domain, all essential for DNA binding and transcriptional regulation. These domains allow ZNF263 to interact with specific DNA sequences, thereby influencing the transcription of target genes. ZNF263 expression across various tissues, including the heart, brain, and liver, highlights ZNF263′s importance in diverse biological processes. ZNF263 monoclonal antibody (8-YD33) enables researchers to gain insights into the regulatory mechanisms of gene expression and potential implications of ZNF263 in various physiological and pathological conditions.

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ZNF263 Antibody (8-YD33) References:

1. Zinc finger proteins: new insights into structural and functional diversity.  |  Laity, JH., et al. 2001. Curr Opin Struct Biol. 11: 39-46. PMID: 11179890
2. The SCAN domain family of zinc finger transcription factors.  |  Edelstein, LC. and Collins, T. 2005. Gene. 359: 1-17. PMID: 16139965
3. Genomic targets of the KRAB and SCAN domain-containing zinc finger protein 263.  |  Frietze, S., et al. 2010. J Biol Chem. 285: 1393-403. PMID: 19887448
4. Multiple genes encoding zinc finger domains are expressed in human T cells.  |  Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
5. Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes.  |  Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
6. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs.  |  Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
7. Isolation of a cDNA encoding a widely expressed novel zinc finger protein with the LeR and KRAB-A domains.  |  Yokoyama, M., et al. 1997. Biochim Biophys Acta. 1353: 13-7. PMID: 9256059

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF263 Antibody (8-YD33) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF263 Antibody (8-YD33) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF263 Antibody (8-YD33) Specifications

Alternate Product Name: ZNF263

Product Clone Name: 8-YD33

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 201-299

Epitope Target: ZNF263

Epitope Species: human

Product Reactivity/Detection: ZNF263

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF263 Antibody (8-YD33): N/A