ZNF207 Antibody (C-6): sc-271943

ZNF207 Antibody (C-6) is a mouse monoclonal IgM antibody that detects ZNF207 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ZNF207 antibody (C-6) is available as the non-conjugated form. ZNF207, also known as zinc finger protein 207, is a 478 amino acid protein that plays a crucial role in the nucleus, where ZNF207 is primarily localized. This nuclear localization is significant as ZNF207 interacts directly with DNA, influencing gene expression and cellular function. ZNF207 contains two C2H2-type zinc fingers, which are essential for DNA-binding capabilities, and is expressed ubiquitously across various tissues, suggesting involvement in fundamental biological processes. ZNF207 may function as a transcription factor, regulating the transcription of target genes, and exists in three isoforms due to alternative splicing events, which may contribute to functional diversity. ZNF207′s ability to modulate transcriptional activity underscores importance in cellular regulation and potential implications in various diseases, making anti-ZNF207 antibody (C-6) a valuable tool for researchers studying gene expression and transcriptional mechanisms.

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ZNF207 Antibody (C-6) References:

1. The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor.  |  Sun, Y., et al. 2003. IUBMB Life. 55: 127-31. PMID: 12822888
2. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.  |  Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
3. A novel subfamily of zinc finger genes involved in embryonic development.  |  Nakamura, M., et al. 2004. J Cell Biochem. 93: 887-95. PMID: 15449319
4. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.  |  O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
5. A Systematic RNAi Screen Reveals a Novel Role of a Spindle Assembly Checkpoint Protein BuGZ in Synaptic Transmission in C. elegans.  |  Han, M., et al. 2017. Front Mol Neurosci. 10: 141. PMID: 28553202
6. Aurora A activation in mitosis promoted by BuGZ.  |  Huang, Y., et al. 2018. J Cell Biol. 217: 107-116. PMID: 29074706
7. Interstitial microdeletion of 17q11.2 is associated with hypotonia, fatigue, intellectual disability, and a subtle facial phenotype in three unrelated patients.  |  Osio, D., et al. 2018. Am J Med Genet A. 176: 209-213. PMID: 29130599
8. Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.  |  Mayer, RL., et al. 2018. Mol Cell Proteomics. 17: 290-303. PMID: 29196338
9. mRNA 5' ends targeted by cytoplasmic recapping cluster at CAGE tags and select transcripts are alternatively spliced.  |  Berger, MR., et al. 2019. FEBS Lett. 593: 670-679. PMID: 30810230
10. ZNF207, a ubiquitously expressed zinc finger gene on chromosome 6p21.3.  |  Pahl, PM., et al. 1998. Genomics. 53: 410-2. PMID: 9799612
11. Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.  |  Rousseau-Merck, MF., et al. 1993. Hum Genet. 92: 583-7. PMID: 8262519
12. The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL.  |  Rousseau-Merck, MF., et al. 2002. Cytogenet Genome Res. 98: 147-53. PMID: 12697996

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF207 Antibody (C-6) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF207 Antibody (C-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF207 Antibody (C-6) Specifications

Alternate Product Name: ZNF207

Product Clone Name: C-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 1-184

Epitope Target: ZNF207

Epitope Species: human

Product Reactivity/Detection: ZNF207

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for ZNF207 Antibody (C-6): N/A